Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
DNA polymerase catalytic subunit
(Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...) | BDBM50091985
(3,5-Dihydroxy-naphthalene-2-carboxylic acid 4-nitr...)Show SMILES Oc1cc2c(O)cccc2cc1C(=O)NCc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H14N2O5/c21-16-3-1-2-12-8-15(17(22)9-14(12)16)18(23)19-10-11-4-6-13(7-5-11)20(24)25/h1-9,21-22H,10H2,(H,19,23) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia
Curated by ChEMBL
| Assay Description Inhibitory activity against Human Cytomegalovirus (HCMV) polymerase |
Bioorg Med Chem Lett 10: 2079-81 (2000)
BindingDB Entry DOI: 10.7270/Q2222T0M |
More data for this Ligand-Target Pair | |
DNA polymerase alpha catalytic subunit
(Homo sapiens (Human)) | BDBM50091985
(3,5-Dihydroxy-naphthalene-2-carboxylic acid 4-nitr...)Show SMILES Oc1cc2c(O)cccc2cc1C(=O)NCc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H14N2O5/c21-16-3-1-2-12-8-15(17(22)9-14(12)16)18(23)19-10-11-4-6-13(7-5-11)20(24)25/h1-9,21-22H,10H2,(H,19,23) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibitory activity against Human alpha polymerase |
Bioorg Med Chem Lett 10: 2079-81 (2000)
BindingDB Entry DOI: 10.7270/Q2222T0M |
More data for this Ligand-Target Pair | |