Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
P2X purinoceptor 1
(Homo sapiens (Human)) | BDBM50430161
(CHEMBL2313134)Show SMILES Oc1ccc(Cl)cc1C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H10ClF6NO2/c17-11-1-2-13(25)12(6-11)14(26)24-7-8-3-9(15(18,19)20)5-10(4-8)16(21,22)23/h1-6,25H,7H2,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc... |
J Med Chem 63: 6164-6178 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00435
BindingDB Entry DOI: 10.7270/Q24F1V93 |
More data for this
Ligand-Target Pair | |
Transmembrane protease serine 4
(Homo sapiens (Human)) | BDBM50430161
(CHEMBL2313134)Show SMILES Oc1ccc(Cl)cc1C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H10ClF6NO2/c17-11-1-2-13(25)12(6-11)14(26)24-7-8-3-9(15(18,19)20)5-10(4-8)16(21,22)23/h1-6,25H,7H2,(H,24,26) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch... |
Bioorg Med Chem Lett 23: 1748-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.055
BindingDB Entry DOI: 10.7270/Q2057H8S |
More data for this
Ligand-Target Pair | |