Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lanosterol synthase
(Rattus norvegicus) | BDBM50450454
(CHEMBL4174978)Show InChI InChI=1S/C20H20N2O3S/c23-18-10-11-19(17-9-4-12-21-20(17)18)26(24,25)22-13-5-8-16(22)14-15-6-2-1-3-7-15/h1-4,6-7,9-12,16,23H,5,8,13-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Lieber Institute for Brain Development
Curated by ChEMBL
| Assay Description Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p... |
J Med Chem 61: 9647-9665 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01126 BindingDB Entry DOI: 10.7270/Q2N300H8 |
More data for this Ligand-Target Pair | |
Lanosterol synthase
(Rattus norvegicus) | BDBM50450454
(CHEMBL4174978)Show InChI InChI=1S/C20H20N2O3S/c23-18-10-11-19(17-9-4-12-21-20(17)18)26(24,25)22-13-5-8-16(22)14-15-6-2-1-3-7-15/h1-4,6-7,9-12,16,23H,5,8,13-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lieber Institute for Brain Development
Curated by ChEMBL
| Assay Description Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra... |
J Med Chem 61: 9647-9665 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01126 BindingDB Entry DOI: 10.7270/Q2N300H8 |
More data for this Ligand-Target Pair | |