Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50057233
((E)-1-[2-Hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-3-[4...)Show SMILES Oc1ccc(cc1C(=O)C=Cc1ccc(OCc2ccc3ccccc3n2)cc1)-c1nnn[nH]1 |w:10.11| Show InChI InChI=1S/C26H19N5O3/c32-24(22-15-19(9-14-25(22)33)26-28-30-31-29-26)13-7-17-5-11-21(12-6-17)34-16-20-10-8-18-3-1-2-4-23(18)27-20/h1-15,33H,16H2,(H,28,29,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50057233
((E)-1-[2-Hydroxy-5-(1H-tetrazol-5-yl)-phenyl]-3-[4...)Show SMILES Oc1ccc(cc1C(=O)C=Cc1ccc(OCc2ccc3ccccc3n2)cc1)-c1nnn[nH]1 |w:10.11| Show InChI InChI=1S/C26H19N5O3/c32-24(22-15-19(9-14-25(22)33)26-28-30-31-29-26)13-7-17-5-11-21(12-6-17)34-16-20-10-8-18-3-1-2-4-23(18)27-20/h1-15,33H,16H2,(H,28,29,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit
Curated by ChEMBL
| Assay Description
Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes |
J Med Chem 40: 1075-89 (1997)
Article DOI: 10.1021/jm960628d
BindingDB Entry DOI: 10.7270/Q25141XJ |
More data for this
Ligand-Target Pair | |