Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM287731
(US10085984, Example 109 | US11040034, Ex. No. 109)Show InChI InChI=1S/C15H12F2N4O/c16-14(17)12-5-8(7-18-20-12)15-19-11-4-3-10(22)6-13(11)21(15)9-1-2-9/h3-7,9,14,22H,1-2H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals (Bermuda), Ltd.
US Patent
| Assay Description V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t... |
US Patent US10085984 (2018)
BindingDB Entry DOI: 10.7270/Q2542QM2 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM287731
(US10085984, Example 109 | US11040034, Ex. No. 109)Show InChI InChI=1S/C15H12F2N4O/c16-14(17)12-5-8(7-18-20-12)15-19-11-4-3-10(22)6-13(11)21(15)9-1-2-9/h3-7,9,14,22H,1-2H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2BV7KRW |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM287731
(US10085984, Example 109 | US11040034, Ex. No. 109)Show InChI InChI=1S/C15H12F2N4O/c16-14(17)12-5-8(7-18-20-12)15-19-11-4-3-10(22)6-13(11)21(15)9-1-2-9/h3-7,9,14,22H,1-2H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2BV7KRW |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM287731
(US10085984, Example 109 | US11040034, Ex. No. 109)Show InChI InChI=1S/C15H12F2N4O/c16-14(17)12-5-8(7-18-20-12)15-19-11-4-3-10(22)6-13(11)21(15)9-1-2-9/h3-7,9,14,22H,1-2H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals (Bermuda), Ltd.
US Patent
| Assay Description V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t... |
US Patent US10085984 (2018)
BindingDB Entry DOI: 10.7270/Q2542QM2 |
More data for this Ligand-Target Pair | |