Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lanosterol synthase
(Rattus norvegicus) | BDBM50529571
(CHEMBL4453736)Show InChI InChI=1S/C15H15ClN2O2/c16-13-4-2-1-3-11(13)8-17-5-6-18-10-15(20)14(19)7-12(18)9-17/h1-4,7,10,20H,5-6,8-9H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Lieber Institute for Brain Development
Curated by ChEMBL
| Assay Description Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ... |
ACS Med Chem Lett 10: 1573-1578 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00345 BindingDB Entry DOI: 10.7270/Q2HD8047 |
More data for this Ligand-Target Pair | |
Lanosterol synthase
(Rattus norvegicus) | BDBM50529571
(CHEMBL4453736)Show InChI InChI=1S/C15H15ClN2O2/c16-13-4-2-1-3-11(13)8-17-5-6-18-10-15(20)14(19)7-12(18)9-17/h1-4,7,10,20H,5-6,8-9H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lieber Institute for Brain Development
Curated by ChEMBL
| Assay Description Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ... |
ACS Med Chem Lett 10: 1573-1578 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00345 BindingDB Entry DOI: 10.7270/Q2HD8047 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50529571
(CHEMBL4453736)Show InChI InChI=1S/C15H15ClN2O2/c16-13-4-2-1-3-11(13)8-17-5-6-18-10-15(20)14(19)7-12(18)9-17/h1-4,7,10,20H,5-6,8-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lieber Institute for Brain Development
Curated by ChEMBL
| Assay Description Inhibition of MAO-B (unknown origin) |
ACS Med Chem Lett 10: 1573-1578 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00345 BindingDB Entry DOI: 10.7270/Q2HD8047 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50529571
(CHEMBL4453736)Show InChI InChI=1S/C15H15ClN2O2/c16-13-4-2-1-3-11(13)8-17-5-6-18-10-15(20)14(19)7-12(18)9-17/h1-4,7,10,20H,5-6,8-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lieber Institute for Brain Development
Curated by ChEMBL
| Assay Description Inhibition of MAO-A (unknown origin) |
ACS Med Chem Lett 10: 1573-1578 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00345 BindingDB Entry DOI: 10.7270/Q2HD8047 |
More data for this Ligand-Target Pair | |