Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 283.2 BDBM50117809

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D-amino-acid oxidase (Homo sapiens (Human))	BDBM50117809 (CHEMBL3613922 | US9505753, 5n) Show SMILES Oc1nn(CCc2cccc3ccccc23)c(=O)[nH]c1=O Show InChI InChI=1S/C15H13N3O3/c19-13-14(20)17-18(15(21)16-13)9-8-11-6-3-5-10-4-1-2-7-12(10)11/h1-7H,8-9H2,(H,17,20)(H,16,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen p...				J Med Chem 58: 7258-72 (2015) Article DOI: 10.1021/acs.jmedchem.5b00482 BindingDB Entry DOI: 10.7270/Q2SF2XZQ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM50117809 (CHEMBL3613922 | US9505753, 5n) Show SMILES Oc1nn(CCc2cccc3ccccc23)c(=O)[nH]c1=O Show InChI InChI=1S/C15H13N3O3/c19-13-14(20)17-18(15(21)16-13)9-8-11-6-3-5-10-4-1-2-7-12(10)11/h1-7H,8-9H2,(H,17,20)(H,16,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	8.5	25
THE JOHNS HOPKINS UNIVERSITY US Patent					Assay Description A reliable 96-well plate D-amino acid oxidase (DAAO) assay was developed based on previously published reports (J. Biol. Chem. 277: 27782 (2002)). Br...				US Patent US9505753 (2016) BindingDB Entry DOI: 10.7270/Q21J98QK
					More data for this Ligand-Target Pair