Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50388282
(CHEMBL2058236)Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccc(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C33H39NO11S/c1-40-28-15-12-22(18-30(28)42-3)11-14-27(23-8-7-9-24(19-23)44-21-32(35)36)45-33(37)26-10-5-6-17-34(26)46(38,39)25-13-16-29(41-2)31(20-25)43-4/h7-9,12-13,15-16,18-20,26-27H,5-6,10-11,14,17,21H2,1-4H3,(H,35,36)/t26-,27+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Institute of Psychiatry
Curated by ChEMBL
| Assay Description Binding affinity to FKBP12 by competitive fluorescence polarization assay |
J Med Chem 55: 4123-31 (2012)
Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP5
(Homo sapiens (Human)) | BDBM50388282
(CHEMBL2058236)Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccc(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C33H39NO11S/c1-40-28-15-12-22(18-30(28)42-3)11-14-27(23-8-7-9-24(19-23)44-21-32(35)36)45-33(37)26-10-5-6-17-34(26)46(38,39)25-13-16-29(41-2)31(20-25)43-4/h7-9,12-13,15-16,18-20,26-27H,5-6,10-11,14,17,21H2,1-4H3,(H,35,36)/t26-,27+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Institute of Psychiatry
Curated by ChEMBL
| Assay Description Binding affinity to FKBP51 FK1 domain by competitive fluorescence polarization assay |
J Med Chem 55: 4123-31 (2012)
Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP4
(Homo sapiens (Human)) | BDBM50388282
(CHEMBL2058236)Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccc(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C33H39NO11S/c1-40-28-15-12-22(18-30(28)42-3)11-14-27(23-8-7-9-24(19-23)44-21-32(35)36)45-33(37)26-10-5-6-17-34(26)46(38,39)25-13-16-29(41-2)31(20-25)43-4/h7-9,12-13,15-16,18-20,26-27H,5-6,10-11,14,17,21H2,1-4H3,(H,35,36)/t26-,27+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Institute of Psychiatry
Curated by ChEMBL
| Assay Description Binding affinity to FKBP52 FK1 domain by competitive fluorescence polarization assay |
J Med Chem 55: 4123-31 (2012)
Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV |
More data for this Ligand-Target Pair | |