Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peptidyl-prolyl cis-trans isomerase FKBP1A
(Homo sapiens (Human)) | BDBM50388292
(CHEMBL2058499)Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cc3CCOc3c(N)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C33H38N2O10S/c1-41-29-12-10-21(16-30(29)42-2)9-11-28(22-6-5-7-24(17-22)44-20-31(36)37)45-33(38)27-8-3-4-14-35(27)46(39,40)25-18-23-13-15-43-32(23)26(34)19-25/h5-7,10,12,16-19,27-28H,3-4,8-9,11,13-15,20,34H2,1-2H3,(H,36,37)/t27-,28+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Institute of Psychiatry
Curated by ChEMBL
| Assay Description Binding affinity to FKBP12 by competitive fluorescence polarization assay |
J Med Chem 55: 4123-31 (2012)
Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP5
(Homo sapiens (Human)) | BDBM50388292
(CHEMBL2058499)Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cc3CCOc3c(N)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C33H38N2O10S/c1-41-29-12-10-21(16-30(29)42-2)9-11-28(22-6-5-7-24(17-22)44-20-31(36)37)45-33(38)27-8-3-4-14-35(27)46(39,40)25-18-23-13-15-43-32(23)26(34)19-25/h5-7,10,12,16-19,27-28H,3-4,8-9,11,13-15,20,34H2,1-2H3,(H,36,37)/t27-,28+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Institute of Psychiatry
Curated by ChEMBL
| Assay Description Binding affinity to FKBP51 FK1 domain by competitive fluorescence polarization assay |
J Med Chem 55: 4123-31 (2012)
Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV |
More data for this Ligand-Target Pair | |
Peptidyl-prolyl cis-trans isomerase FKBP4
(Homo sapiens (Human)) | BDBM50388292
(CHEMBL2058499)Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cc3CCOc3c(N)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C33H38N2O10S/c1-41-29-12-10-21(16-30(29)42-2)9-11-28(22-6-5-7-24(17-22)44-20-31(36)37)45-33(38)27-8-3-4-14-35(27)46(39,40)25-18-23-13-15-43-32(23)26(34)19-25/h5-7,10,12,16-19,27-28H,3-4,8-9,11,13-15,20,34H2,1-2H3,(H,36,37)/t27-,28+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Institute of Psychiatry
Curated by ChEMBL
| Assay Description Binding affinity to FKBP52 FK1 domain by competitive fluorescence polarization assay |
J Med Chem 55: 4123-31 (2012)
Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV |
More data for this Ligand-Target Pair | |