Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (Homo sapiens) | BDBM50587492![]() (CHEMBL5079107) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant BCKDK incubated for 60 mins in presence of ATP by ADP-Glo reagent based luminescent assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (Homo sapiens) | BDBM50587493![]() (CHEMBL5087238) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant BCKDK incubated for 60 mins in presence of ATP by ADP-Glo reagent based luminescent assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (Homo sapiens) | BDBM50587479![]() (CHEMBL5082649) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant BCKDK incubated for 60 mins in presence of ATP by ADP-Glo reagent based luminescent assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (Homo sapiens) | BDBM50571963![]() (CHEMBL4855768) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant BCKDK incubated for 60 mins by ADP-Glo kinase assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116283 BindingDB Entry DOI: 10.7270/Q22V2KXR | |||||||||||
More data for this Ligand-Target Pair |