Compile Data Set for Download or QSAR

Found 185 hits Enz. Inhib. hit(s) with Target = '1-phosphatidylinositol 3-phosphate 5-kinase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.309	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.312	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590928 (CHEMBL2178735) Show SMILES Nc1ccc(cn1)C(=O)Nc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM50590929 (CHEMBL4303292 | US20240016810, Compound TABLE 16.2) Show SMILES Cc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590929 (CHEMBL4303292 | US20240016810, Compound TABLE 16.2) Show SMILES Cc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590929 (CHEMBL4303292 | US20240016810, Compound TABLE 16.2) Show SMILES Cc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590943 (CHEMBL5189479) Show SMILES CCC(O)(CC)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590942 (CHEMBL5193848) Show SMILES CCC(C)(O)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50429615 (CHEMBL2334586) Show SMILES CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI InChI=1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50429615 (CHEMBL2334586) Show SMILES CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI InChI=1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590929 (CHEMBL4303292 | US20240016810, Compound TABLE 16.2) Show SMILES Cc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590939 (CHEMBL5174830) Show SMILES CN(C)CC#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590939 (CHEMBL5174830) Show SMILES CN(C)CC#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590956 (CHEMBL5171359) Show SMILES CC(O)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645378 (US20240016810, Compound TABLE 15.3 | US20240016810...) Show SMILES Cc1cccc(\C=N\Nc2nc(N3CCOCC3)c3nc(-c4ccncc4)n(C)c3n2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645378 (US20240016810, Compound TABLE 15.3 | US20240016810...) Show SMILES Cc1cccc(\C=N\Nc2nc(N3CCOCC3)c3nc(-c4ccncc4)n(C)c3n2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590931 (CHEMBL5181163) Show SMILES CC(C)(O)C#Cc1ccc2[nH]cc(-c3ccnc(N)n3)c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590941 (CHEMBL5198944) Show SMILES COC(C)(C)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590939 (CHEMBL5174830) Show SMILES CN(C)CC#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645389 (US20240016810, Compound TABLE 16.3) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccc(CN)cc3)n2)N2CCOCC2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM50590929 (CHEMBL4303292 | US20240016810, Compound TABLE 16.2) Show SMILES Cc1cccc(\C=N\Nc2cc(N3CCOCC3)n3nc(cc3n2)-c2ccncc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590934 (CHEMBL5207387) Show SMILES Nc1ncc2CCc3[nH]c4ccc(cc4c3-c2n1)-c1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50595937 (CHEMBL5194705) Show SMILES Ic1cccc(\C=N\Nc2nc(nc(n2)N2CCOCC2)N(c2ccccc2)c2ccccc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00302 BindingDB Entry DOI: 10.7270/Q20Z779V
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590935 (CHEMBL5171753) Show SMILES Nc1ncc2CCCc3[nH]c4ccc(cc4c3-c2n1)-c1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590942 (CHEMBL5193848) Show SMILES CCC(C)(O)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590935 (CHEMBL5171753) Show SMILES Nc1ncc2CCCc3[nH]c4ccc(cc4c3-c2n1)-c1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590935 (CHEMBL5171753) Show SMILES Nc1ncc2CCCc3[nH]c4ccc(cc4c3-c2n1)-c1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645377 (US20240016810, Compound TABLE 15.2) Show SMILES Cc1cccc(\C=N\Nc2cc(N3CC4CC3CO4)n3nc(cc3n2)-c2ccncc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590943 (CHEMBL5189479) Show SMILES CCC(O)(CC)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590943 (CHEMBL5189479) Show SMILES CCC(O)(CC)c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50429615 (CHEMBL2334586) Show SMILES CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI InChI=1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645392 (US20240016810, Compound TABLE 16.5) Show SMILES C1CN(CCO1)c1cc(nc2cc(nn12)-c1ccncc1)-c1cccc(n1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00302 BindingDB Entry DOI: 10.7270/Q20Z779V
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01467 BindingDB Entry DOI: 10.7270/Q24Q801K
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590927 (APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...) Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01467 BindingDB Entry DOI: 10.7270/Q24Q801K
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645401 (US20240016810, Compound TABLE 16.14) Show SMILES Cc1cccc(\C=N\Nc2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645399 (US20240016810, Compound TABLE 16.12) Show SMILES Oc1cc(nn1-c1cc(N2CCOCC2)n2nc(nc2n1)-c1ccncc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590931 (CHEMBL5181163) Show SMILES CC(C)(O)C#Cc1ccc2[nH]cc(-c3ccnc(N)n3)c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590932 (CHEMBL5190524) Show SMILES Nc1ncc2CCCc3[nH]c4ccc(cc4c3-c2n1)C#Cc1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590937 (CHEMBL5188159) Show SMILES Cn1cc(cn1)-c1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645402 (US20240016810, Compound TABLE 16.15) Show SMILES C(Oc1nc(cc(n1)-c1nccc(n1)-c1ccccc1)N1CCOCC1)c1ccncc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590928 (CHEMBL2178735) Show SMILES Nc1ccc(cn1)C(=O)Nc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00302 BindingDB Entry DOI: 10.7270/Q20Z779V
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590928 (CHEMBL2178735) Show SMILES Nc1ccc(cn1)C(=O)Nc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590936 (CHEMBL5200109) Show SMILES Cn1cc(cn1)-c1ccc2[nH]c3CCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50511422 (CHEMBL4446338) Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2cc(ncn2)-c2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C31H29N7O2/c1-38(2)16-6-11-30(39)36-22-14-12-21(13-15-22)31(40)37-24-8-5-7-23(17-24)35-29-18-28(33-20-34-29)26-19-32-27-10-4-3-9-25(26)27/h3-15,17-20,32H,16H2,1-2H3,(H,36,39)(H,37,40)(H,33,34,35)/b11-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged full length human PIKFYVE (1 to 2098 residues) using PI(3)P and Phosphatidylserine as substrate by ADP-Glo assay				ACS Med Chem Lett 11: 346-352 (2020) Article DOI: 10.1021/acsmedchemlett.9b00402 BindingDB Entry DOI: 10.7270/Q2TM7FDP
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590957 (CHEMBL5185288) Show SMILES Nc1ncc2CCCc3[nH]c4ccc(CCO)cc4c3-c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932S,Q995L,T998S,S1033A,Q1183K] (Homo sapiens (Human))	BDBM645407 (US20240016810, Compound TABLE 16.20) Show SMILES C(Oc1nc(nc2N(CCc12)c1ccccc1)N1CCOCC1)c1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
1-phosphatidylinositol 3-phosphate 5-kinase (Homo sapiens)	BDBM50590952 (CHEMBL5190153) Show SMILES CC(C)C(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair

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