Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292583![]() (CHEMBL4164794) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292582![]() (CHEMBL4162427) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292585![]() (CHEMBL4161382) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292584![]() (CHEMBL4172694) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292590![]() (CHEMBL4162165) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292586![]() (CHEMBL4169301) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292580![]() (CHEMBL4172838) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 7.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292589![]() (CHEMBL4159624) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.59E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292587![]() (CHEMBL4167547) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.89E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292581![]() (CHEMBL4165870) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Competitive inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by Lineweaver-Burk plot analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50396489![]() (CHEMBL2170943) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Competitive inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by Lineweaver-Burk plot analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair |