Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM205431 ((6S+2S)-PEG1 (7)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.00690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute | Assay Description Refer to DiscoverX | Nat Chem Biol 12: 1089-1096 (2016) Article DOI: 10.1038/nchembio.2209 BindingDB Entry DOI: 10.7270/Q2VQ31HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM205453 (MTI (35)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute | Assay Description Refer to DiscoverX | Nat Chem Biol 12: 1089-1096 (2016) Article DOI: 10.1038/nchembio.2209 BindingDB Entry DOI: 10.7270/Q2VQ31HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM50452557 (CHEMBL4206677 | US11028051, Cmpd 55) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM50452554 (CHEMBL4207106 | US11028051, Cmpd 51) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM50452552 (CHEMBL4205876 | US11028051, Cmpd 52) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM50452556 (CHEMBL4210405 | US11028051, Cmpd 53) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM50452553 (CHEMBL4202664 | US11028051, Cmpd 54) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM205429 ( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM205429 ( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute | Assay Description Refer to DiscoverX | Nat Chem Biol 12: 1089-1096 (2016) Article DOI: 10.1038/nchembio.2209 BindingDB Entry DOI: 10.7270/Q2VQ31HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [348-455] (Homo sapiens (Human)) | BDBM50452551 (CHEMBL4209110 | US11028051, Cmpd 50) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair |