Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2 [424-538]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321463 (6-(but-3-en-1-yl)-4-(3-(difluoromethoxy)-5-(morpho...) Show SMILES FC(F)Oc1cc(cc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H23F2N3O4/c1-2-3-6-28-14-19(18-4-5-26-20(18)22(28)30)15-11-16(13-17(12-15)32-23(24)25)21(29)27-7-9-31-10-8-27/h2,4-5,11-14,23,26H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321462 (6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...) Show SMILES Fc1ccc(cc1C(=O)N1CCOCC1)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H22FN3O3/c1-2-3-8-26-14-18(16-6-7-24-20(16)22(26)28)15-4-5-19(23)17(13-15)21(27)25-9-11-29-12-10-25/h2,4-7,13-14,24H,1,3,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321476 (6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...) Show SMILES Cc1cc2c(cn(CCC=C)c(=O)c2[nH]1)-c1ccc(F)c(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H24FN3O3/c1-3-4-7-27-14-19(17-12-15(2)25-21(17)23(27)29)16-5-6-20(24)18(13-16)22(28)26-8-10-30-11-9-26/h3,5-6,12-14,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321470 (6-but-3-enyl-4-[1-methyl-6-(morpholine-4-carbonyl)...) Show SMILES Cn1cnc2c(cc(cc12)C(=O)N1CCOCC1)-n1cc(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C24H25N5O3/c1-3-4-5-16-14-29(18-6-7-25-22(18)23(16)30)20-13-17(12-19-21(20)26-15-27(19)2)24(31)28-8-10-32-11-9-28/h3,6-7,12-15,25H,1,4-5,8-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321465 (6-but-3-enyl-4-[3-methyl-7-(morpholine-4-carbonyl)...) Show SMILES Cn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)16-12-18(21-20(13-16)27(2)15-26-21)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321465 (6-but-3-enyl-4-[3-methyl-7-(morpholine-4-carbonyl)...) Show SMILES Cn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)16-12-18(21-20(13-16)27(2)15-26-21)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321474 (6-but-3-enyl-4-[4-chloro-3-(morpholine-4-carbonyl)...) Show SMILES Cc1cc2c(cn(CCC=C)c(=O)c2[nH]1)-c1ccc(Cl)c(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H24ClN3O3/c1-3-4-7-27-14-19(17-12-15(2)25-21(17)23(27)29)16-5-6-20(24)18(13-16)22(28)26-8-10-30-11-9-26/h3,5-6,12-14,25H,1,4,7-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321468 (6-but-3-enyl-4-[6-(morpholine-4-carbonyl)-1H-benzi...) Show SMILES C=CCCn1cc(-c2cc(cc3[nH]cnc23)C(=O)N2CCOCC2)c2cc[nH]c2c1=O Show InChI InChI=1S/C23H23N5O3/c1-2-3-6-28-13-18(16-4-5-24-21(16)23(28)30)17-11-15(12-19-20(17)26-14-25-19)22(29)27-7-9-31-10-8-27/h2,4-5,11-14,24H,1,3,6-10H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321475 (6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...) Show SMILES Cc1cc2c(cn(CCC=C)c(=O)c2[nH]1)-c1cc(F)cc(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H24FN3O3/c1-3-4-5-27-14-20(19-10-15(2)25-21(19)23(27)29)16-11-17(13-18(24)12-16)22(28)26-6-8-30-9-7-26/h3,10-14,25H,1,4-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321467 (6-but-3-enyl-4-[3-ethyl-7-(morpholine-4-carbonyl)b...) Show SMILES CCn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C25H27N5O3/c1-3-5-8-30-15-20(18-6-7-26-23(18)25(30)32)17-13-19(24(31)29-9-11-33-12-10-29)22-21(14-17)28(4-2)16-27-22/h3,6-7,13-16,26H,1,4-5,8-12H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321458 (6-but-3-enyl-4-[3,4-difluoro-5-(morpholine-4-carbo...) Show SMILES Fc1cc(cc(C(=O)N2CCOCC2)c1F)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H21F2N3O3/c1-2-3-6-27-13-17(15-4-5-25-20(15)22(27)29)14-11-16(19(24)18(23)12-14)21(28)26-7-9-30-10-8-26/h2,4-5,11-13,25H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321459 (6-but-3-enyl-4-[3-fluoro-5-(3-methylmorpholine-4-c...) Show SMILES CC1COCCN1C(=O)c1cc(F)cc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321461 (6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...) Show SMILES Fc1cc(cc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H22FN3O3/c1-2-3-6-26-14-19(18-4-5-24-20(18)22(26)28)15-11-16(13-17(23)12-15)21(27)25-7-9-29-10-8-25/h2,4-5,11-14,24H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321469 (4-(6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[...) Show SMILES CN(C)C(=O)c1cc(-c2cn(CCC=C)c(=O)c3[nH]ccc23)c2nc[nH]c2c1 Show InChI InChI=1S/C21H21N5O2/c1-4-5-8-26-11-16(14-6-7-22-19(14)21(26)28)15-9-13(20(27)25(2)3)10-17-18(15)24-12-23-17/h4,6-7,9-12,22H,1,5,8H2,2-3H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321460 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES C=CCCn1cc(-c2cc(cc(c2)C(=O)N2CCOCC2)C#N)c2cc[nH]c2c1=O Show InChI InChI=1S/C23H22N4O3/c1-2-3-6-27-15-20(19-4-5-25-21(19)23(27)29)17-11-16(14-24)12-18(13-17)22(28)26-7-9-30-10-8-26/h2,4-5,11-13,15,25H,1,3,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321464 (6-but-3-enyl-4-[7-(morpholine-4-carbonyl)-3H-benzi...) Show SMILES C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)c3nc[nH]c3c2)c2cc[nH]c2c1=O Show InChI InChI=1S/C23H23N5O3/c1-2-3-6-28-13-18(16-4-5-24-21(16)23(28)30)15-11-17(20-19(12-15)25-14-26-20)22(29)27-7-9-31-10-8-27/h2,4-5,11-14,24H,1,3,6-10H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310905 (2-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...) Show SMILES CC1Oc2cc(ccc2NC1=O)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310911 (6-methyl-4-(2-methyl-3,4-dihydro-1H-isoquinolin-6-...) Show SMILES Cn1cc(-c2ccc3CNCCc3c2)c2cc[nH]c2c1=O Show InChI InChI=1S/C17H17N3O/c1-20-10-15(14-5-7-19-16(14)17(20)21)12-2-3-13-9-18-6-4-11(13)8-12/h2-3,5,7-8,10,18-19H,4,6,9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310910 (4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N...) Show SMILES Cn1cc(-c2ccc(cc2)C(=O)Nc2ccccc2)c2cc[nH]c2c1=O Show InChI InChI=1S/C21H17N3O2/c1-24-13-18(17-11-12-22-19(17)21(24)26)14-7-9-15(10-8-14)20(25)23-16-5-3-2-4-6-16/h2-13,22H,1H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321452 (6-but-3-enyl-4-[3-(5-methyl-1,3,4-oxadiazol-2-yl)p...) Show SMILES Cc1nnc(o1)-c1cccc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H18N4O2/c1-3-4-10-24-12-17(16-8-9-21-18(16)20(24)25)14-6-5-7-15(11-14)19-23-22-13(2)26-19/h3,5-9,11-12,21H,1,4,10H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1cn(CCC=C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H21N3O2/c1-4-5-11-23-13-17(16-9-10-21-18(16)20(23)25)14-7-6-8-15(12-14)19(24)22(2)3/h4,6-10,12-13,21H,1,5,11H2,2-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310912 (3-(2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1cn(C)c(=O)c2[nH]c(C)cc12 Show InChI InChI=1S/C18H19N3O2/c1-11-8-14-15(10-21(4)18(23)16(14)19-11)12-6-5-7-13(9-12)17(22)20(2)3/h5-10,19H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310909 (4-[4-(3,3-difluoroazetidine-1-carbonyl)phenyl]-6-m...) Show SMILES Cn1cc(-c2ccc(cc2)C(=O)N2CC(F)(F)C2)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H15F2N3O2/c1-22-8-14(13-6-7-21-15(13)17(22)25)11-2-4-12(5-3-11)16(24)23-9-18(19,20)10-23/h2-8,21H,9-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310904 (3-methoxy-N-[4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...) Show SMILES COCCC(=O)Nc1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C18H19N3O3/c1-21-11-15(14-7-9-19-17(14)18(21)23)12-3-5-13(6-4-12)20-16(22)8-10-24-2/h3-7,9,11,19H,8,10H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310908 (6-methyl-4-(4-(4-methyl-3-oxopiperazine-1-carbonyl...) Show SMILES CN1CCN(CC1=O)C(=O)c1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H20N4O3/c1-22-9-10-24(12-17(22)25)19(26)14-5-3-13(4-6-14)16-11-23(2)20(27)18-15(16)7-8-21-18/h3-8,11,21H,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321473 (3-(6-(2-cyclopropylethyl)-2-methyl-7-oxo-6,7-dihyd...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1cn(CCC2CC2)c(=O)c2[nH]c(C)cc12 Show InChI InChI=1S/C22H25N3O2/c1-14-11-18-19(16-5-4-6-17(12-16)21(26)24(2)3)13-25(10-9-15-7-8-15)22(27)20(18)23-14/h4-6,11-13,15,23H,7-10H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321453 (3-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES CNC(=O)c1cccc(c1)-c1cn(CC=CC)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C19H19N3O2/c1-3-4-10-22-12-16(15-8-9-21-17(15)19(22)24)13-6-5-7-14(11-13)18(23)20-2/h3-9,11-12,21H,10H2,1-2H3,(H,20,23)/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310906 (N,N-dimethyl-4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C17H17N3O2/c1-19(2)16(21)12-6-4-11(5-7-12)14-10-20(3)17(22)15-13(14)8-9-18-15/h4-10,18H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321472 (4-[5-(6-acetyl-2,6-diazaspiro[3.3]heptane-2-carbon...) Show SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(=O)N1CC2(CN(C2)C(C)=O)C1 Show InChI InChI=1S/C26H28N4O4/c1-4-5-10-28-12-21(19-8-9-27-23(19)25(28)33)20-11-18(6-7-22(20)34-3)24(32)30-15-26(16-30)13-29(14-26)17(2)31/h4-9,11-12,27H,10,13-16H2,1-3H3/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310907 (3-(6-ethyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,...) Show SMILES CCn1cc(-c2cccc(c2)C(=O)N(C)C)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H19N3O2/c1-4-21-11-15(14-8-9-19-16(14)18(21)23)12-6-5-7-13(10-12)17(22)20(2)3/h5-11,19H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321456 (4-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(N)=O)c(Cl)c2)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H16ClN3O2/c1-2-3-8-22-10-14(12-6-7-21-16(12)18(22)24)11-4-5-13(17(20)23)15(19)9-11/h2-7,9-10,21H,8H2,1H3,(H2,20,23)/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321471 (4-[5-(azetidine-1-carbonyl)-2-methoxy-phenyl]-6-[(...) Show SMILES COc1ccc(cc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(=O)N1CCC1 Show InChI InChI=1S/C22H23N3O3/c1-3-4-10-25-14-18(16-8-9-23-20(16)22(25)27)17-13-15(6-7-19(17)28-2)21(26)24-11-5-12-24/h3-4,6-9,13-14,23H,5,10-12H2,1-2H3/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321449 (3-[6-(2-methoxyethyl)-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES COCCn1cc(-c2cccc(c2)C(=O)N(C)C)c2cc[nH]c2c1=O Show InChI InChI=1S/C19H21N3O3/c1-21(2)18(23)14-6-4-5-13(11-14)16-12-22(9-10-25-3)19(24)17-15(16)7-8-20-17/h4-8,11-12,20H,9-10H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321455 (4-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...) Show SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N(C)C)c(Cl)c2)c2cc[nH]c2c1=O Show InChI InChI=1S/C20H20ClN3O2/c1-4-5-10-24-12-16(14-8-9-22-18(14)20(24)26)13-6-7-15(17(21)11-13)19(25)23(2)3/h4-9,11-12,22H,10H2,1-3H3/b5-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321457 (3-[6-(2-cyclopropylethyl)-7-oxo-1H-pyrrolo[2,3-c]p...) Show SMILES COc1ccc(cc1-c1cn(CCC2CC2)c(=O)c2[nH]ccc12)C#N Show InChI InChI=1S/C20H19N3O2/c1-25-18-5-4-14(11-21)10-16(18)17-12-23(9-7-13-2-3-13)20(24)19-15(17)6-8-22-19/h4-6,8,10,12-13,22H,2-3,7,9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321454 (6-but-2-enyl-4-[4-(hydroxymethyl)phenyl]-1H-pyrrol...) Show SMILES CC=CCn1cc(-c2ccc(CO)cc2)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H18N2O2/c1-2-3-10-20-11-16(14-6-4-13(12-21)5-7-14)15-8-9-19-17(15)18(20)22/h2-9,11,19,21H,10,12H2,1H3/b3-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321447 (N,N-dimethyl-3-[6-(3-methylbut-2-enyl)-7-oxo-1H-py...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1cn(CC=C(C)C)c(=O)c2[nH]ccc12 |(-2.52,-1.54,;-2.52,-3.08,;-3.85,-3.85,;-1.18,-3.85,;-1.18,-5.39,;.15,-3.08,;1.48,-3.85,;2.82,-3.08,;2.82,-1.54,;1.48,-.77,;.15,-1.54,;1.48,.77,;.15,1.54,;.15,3.08,;-1.18,3.85,;-2.52,3.08,;-3.85,3.85,;-3.85,5.39,;-5.19,3.08,;1.48,3.85,;1.48,5.39,;2.82,3.08,;4.28,3.56,;5.19,2.31,;4.28,1.06,;2.82,1.54,)| Show InChI InChI=1S/C21H23N3O2/c1-14(2)9-11-24-13-18(17-8-10-22-19(17)21(24)26)15-6-5-7-16(12-15)20(25)23(3)4/h5-10,12-13,22H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321451 (3-[6-(cyclopropylmethyl)-7-oxo-1H-pyrrolo[2,3-c]py...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1cn(CC2CC2)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H21N3O2/c1-22(2)19(24)15-5-3-4-14(10-15)17-12-23(11-13-6-7-13)20(25)18-16(17)8-9-21-18/h3-5,8-10,12-13,21H,6-7,11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM321450 (3-[6-(3-methoxypropyl)-7-oxo-1H-pyrrolo[2,3-c]pyri...) Show SMILES COCCCn1cc(-c2cccc(c2)C(=O)N(C)C)c2cc[nH]c2c1=O Show InChI InChI=1S/C20H23N3O3/c1-22(2)19(24)15-7-4-6-14(12-15)17-13-23(10-5-11-26-3)20(25)18-16(17)8-9-21-18/h4,6-9,12-13,21H,5,10-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10183009 (2019) BindingDB Entry DOI: 10.7270/Q2125VRQ
					More data for this Ligand-Target Pair