Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'GMP synthase [glutamine-hydrolyzing]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GMP synthase [glutamine-hydrolyzing] (Mus musculus)	BDBM50042853 (CHEMBL127366 | N-(4-Isothiocyanatomethyl-thiazol-2...) Show SMILES O=C(Nc1nc(CN=C=S)cs1)c1ccccc1 Show InChI InChI=1S/C12H9N3OS2/c16-11(9-4-2-1-3-5-9)15-12-14-10(7-18-12)6-13-8-17/h1-5,7H,6H2,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description In vitro inhibitory activity against partially purified GMP synthetase in L1210 cells				J Med Chem 36: 3849-52 (1994) BindingDB Entry DOI: 10.7270/Q2W9588K
					More data for this Ligand-Target Pair
GMP synthase [glutamine-hydrolyzing] (Homo sapiens)	BDBM50519499 (CHEBI:8612 | Psicofuranine) Show SMILES Nc1ncnc2n(cnc12)[C@]1(CO)O[C@H](CO)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C11H15N5O5/c12-9-6-10(14-3-13-9)16(4-15-6)11(2-18)8(20)7(19)5(1-17)21-11/h3-5,7-8,17-20H,1-2H2,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Inhibition of human GMP synthase				J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182 BindingDB Entry DOI: 10.7270/Q2T1571N
					More data for this Ligand-Target Pair
GMP synthase [glutamine-hydrolyzing] (Homo sapiens)	BDBM50519498 (Decoyinine) Show SMILES Nc1ncnc2n(cnc12)[C@]1(CO)OC(=C)[C@@H](O)[C@H]1O Show InChI InChI=1S/C11H13N5O4/c1-5-7(18)8(19)11(2-17,20-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-4,7-8,17-19H,1-2H2,(H2,12,13,14)/t7-,8-,11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Inhibition of human GMP synthase				J Med Chem 62: 8365-8391 (2019) Article DOI: 10.1021/acs.jmedchem.9b00182 BindingDB Entry DOI: 10.7270/Q2T1571N
					More data for this Ligand-Target Pair