Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase SETD1B'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SETD1B (Homo sapiens)	BDBM50524882 (CHEMBL4465202) Show SMILES Cc1cc(OCCCC(=O)Nc2ncc(Br)s2)ccc1Cl Show InChI InChI=1S/C14H14BrClN2O2S/c1-9-7-10(4-5-11(9)16)20-6-2-3-13(19)18-14-17-8-12(15)21-14/h4-5,7-8H,2-3,6H2,1H3,(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of C-terminal GST-tagged human SET1B (1629 to 1923 amino acids) expressed in Escherichia coli using core histone as substrate in presence ...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SETD1B (Homo sapiens)	BDBM50508569 (CHEMBL4557353) Show SMILES CCCCOc1ccc(cc1C)S(=O)(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C18H21NO5S/c1-3-4-11-24-17-10-9-16(12-13(17)2)25(22,23)19-15-7-5-14(6-8-15)18(20)21/h5-10,12,19H,3-4,11H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Sci-Tech University Curated by ChEMBL					Assay Description Inhibition of SETD1B (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alpha...				Bioorg Med Chem Lett 29: 638-645 (2019) Article DOI: 10.1016/j.bmcl.2018.12.035 BindingDB Entry DOI: 10.7270/Q26W9FC5
					More data for this Ligand-Target Pair