BindingDB PrimarySearch

Found 23 hits Enz. Inhib. hit(s) with Target = 'Hyaluronidase-1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81868 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81862 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81865 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81866 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81864 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81861 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.32E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81867 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.37E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81860 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES O=C(NCc1ccccc1)c1cc2ccccc2n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.03E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81863 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.11E+4	n/a	n/a	n/a	n/a	7.0	37
TBA					Assay Description Stains-all assay were used to test inhibitors at pH of 7.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81868 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.67E+4	n/a	n/a	n/a	n/a	3.5	37
TBA					Assay Description Morgan-elson assay were used to test inhibitors at pH of 3.5.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81866 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.16E+4	n/a	n/a	n/a	n/a	3.5	37
TBA					Assay Description Morgan-elson assay were used to test inhibitors at pH of 3.5.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81861 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.43E+4	n/a	n/a	n/a	n/a	3.5	37
TBA					Assay Description Morgan-elson assay were used to test inhibitors at pH of 3.5.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81867 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.29E+4	n/a	n/a	n/a	n/a	3.5	37
TBA					Assay Description Morgan-elson assay were used to test inhibitors at pH of 3.5.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM81860 (N-Substituted indole-2- and 3-carboxamide derivati...) Show SMILES O=C(NCc1ccccc1)c1cc2ccccc2n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.82E+4	n/a	n/a	n/a	n/a	3.5	37
TBA					Assay Description Morgan-elson assay were used to test inhibitors at pH of 3.5.				Chem Biol Drug Des 70: 547-51 (2007) Article DOI: 10.1111/j.1747-0285.2007.00590.x BindingDB Entry DOI: 10.7270/Q2FB51F7
TBA					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50316415 (CHEMBL1097937 \| Cimicifugic acid L \| cimicifugic a...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50316417 (CHEMBL1094303 \| Cimicifugic acid N) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50316416 (CHEMBL1096937 \| Cimicifugic acid M) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50316414 (CHEMBL1096631 \| Cimicifugic acid K) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1/Hyaluronidase-2 (Bos taurus )	BDBM50292241 (CHEMBL4159080) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Inhibition of bovine testes hyaluronidase using hyaluronic acid as substrate preincubated for 10 mins in dark followed by incubation with substrate f...				Eur J Med Chem 145: 760-769 (2018) Article DOI: 10.1016/j.ejmech.2018.01.014 BindingDB Entry DOI: 10.7270/Q2WM1GZM
Medical University of Lodz Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50133496 ((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM4375 ((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid \| (2...) Show SMILES OC(=O)\C=C\c1ccc(O)c(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50214744 ((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic aci...) Show SMILES COc1cc(\C=C\C(O)=O)ccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair
Hyaluronidase-1 (Homo sapiens (Human))	BDBM50241245 ((2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic aci...) Show SMILES COc1ccc(\C=C\C(O)=O)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of hyaluronidase				J Nat Prod 73: 609-12 (2010) Article DOI: 10.1021/np900752t BindingDB Entry DOI: 10.7270/Q2GF0TNW
University of Shizuoka Curated by ChEMBL					More data for this Ligand-Target Pair