Compile Data Set for Download or QSAR

Found 17 hits Enz. Inhib. hit(s) with Target = 'Nuclear factor of activated T-cells, cytoplasmic 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50595362 (CHEMBL5174163) Show SMILES Cc1ccc(s1)C(=O)NCC(=O)Nc1cc(ccc1Cl)S(=O)(=O)Nc1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114514 BindingDB Entry DOI: 10.7270/Q2M049GQ
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50595363 (CHEMBL5195853) Show SMILES CS(=O)(=O)NCc1cccc(NC(=O)c2ccc3[nH]ccc3c2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114514 BindingDB Entry DOI: 10.7270/Q2M049GQ
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50595364 (CHEMBL5181607) Show SMILES CS(=O)(=O)NCc1cccc(NC(=O)c2csc3ccccc23)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114514 BindingDB Entry DOI: 10.7270/Q2M049GQ
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251457 (CHEMBL4105629) Show SMILES C(Cn1cc(-c2ccncc2)c2ccncc12)C1CC1 Show InChI InChI=1S/C17H17N3/c1-2-13(1)6-10-20-12-16(14-3-7-18-8-4-14)15-5-9-19-11-17(15)20/h3-5,7-9,11-13H,1-2,6,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251476 (CHEMBL4095674) Show SMILES C(CN1CCOCC1)Cn1cc(-c2ccncc2)c2ccncc12 Show InChI InChI=1S/C19H22N4O/c1(8-22-10-12-24-13-11-22)9-23-15-18(16-2-5-20-6-3-16)17-4-7-21-14-19(17)23/h2-7,14-15H,1,8-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.96E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251477 (CHEMBL4075648) Show SMILES Clc1cnccc1-c1c[nH]c2cnccc12 Show InChI InChI=1S/C12H8ClN3/c13-11-6-14-3-1-8(11)10-5-16-12-7-15-4-2-9(10)12/h1-7,16H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.31E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251475 (CHEMBL4090889) Show SMILES COc1cccc2c(c[nH]c12)-c1ccnc(N)n1 Show InChI InChI=1S/C13H12N4O/c1-18-11-4-2-3-8-9(7-16-12(8)11)10-5-6-15-13(14)17-10/h2-7,16H,1H3,(H2,14,15,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251486 (CHEMBL4066607) Show SMILES c1[nH]c2cnccc2c1-c1ccnc2ccccc12 Show InChI InChI=1S/C16H11N3/c1-2-4-15-12(3-1)11(6-8-18-15)14-9-19-16-10-17-7-5-13(14)16/h1-10,19H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251504 (CHEMBL4098505) Show SMILES Fc1cc(ccn1)-c1c[nH]c2cnccc12 Show InChI InChI=1S/C12H8FN3/c13-12-5-8(1-4-15-12)10-6-16-11-7-14-3-2-9(10)11/h1-7,16H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.85E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251456 (CHEMBL4084955) Show SMILES c1[nH]c2cnccc2c1-c1ccncc1 Show InChI InChI=1S/C12H9N3/c1-4-13-5-2-9(1)11-7-15-12-8-14-6-3-10(11)12/h1-8,15H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251509 (CHEMBL4064316) Show SMILES CC(C)n1cc(-c2ccncc2)c2ccncc12 Show InChI InChI=1S/C15H15N3/c1-11(2)18-10-14(12-3-6-16-7-4-12)13-5-8-17-9-15(13)18/h3-11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251478 (CHEMBL4072138) Show SMILES Nc1nccc(n1)-c1c[nH]c2c(cccc12)C#N Show InChI InChI=1S/C13H9N5/c14-6-8-2-1-3-9-10(7-17-12(8)9)11-4-5-16-13(15)18-11/h1-5,7,17H,(H2,15,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251453 (CHEMBL4079572) Show SMILES Nc1nccc(n1)-c1c[nH]c2cnccc12 Show InChI InChI=1S/C11H9N5/c12-11-14-4-2-9(16-11)8-5-15-10-6-13-3-1-7(8)10/h1-6,15H,(H2,12,14,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251485 (CHEMBL4080488) Show SMILES Cc1cc(ccn1)-c1c[nH]c2cnccc12 Show InChI InChI=1S/C13H11N3/c1-9-6-10(2-5-15-9)12-7-16-13-8-14-4-3-11(12)13/h2-8,16H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251452 (CHEMBL4077010) Show SMILES Cn1cc(-c2ccncc2)c2ccncc12 Show InChI InChI=1S/C13H11N3/c1-16-9-12(10-2-5-14-6-3-10)11-4-7-15-8-13(11)16/h2-9H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251436 (CHEMBL4091320) Show SMILES COCCn1cc(-c2ccncc2)c2ccncc12 Show InChI InChI=1S/C15H15N3O/c1-19-9-8-18-11-14(12-2-5-16-6-3-12)13-4-7-17-10-15(13)18/h2-7,10-11H,8-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair
Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens)	BDBM50251451 (CHEMBL4069163) Show SMILES Fc1ccc(Cn2cc(-c3ccncc3)c3ccncc23)cc1 Show InChI InChI=1S/C19H14FN3/c20-16-3-1-14(2-4-16)12-23-13-18(15-5-8-21-9-6-15)17-7-10-22-11-19(17)23/h1-11,13H,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.58E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair