Found 1682 hits Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616687
(US20230278998, Compound 5)Show SMILES CC(C)C(=O)N1CCN(CC1)c1cc(cc2c(nn(C)c12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(C)CC1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616699
(US20230278998, Compound 17)Show SMILES CC(C)C(=O)N1CCN(CC1)c1cc(cc2c(nn(C)c12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(CC1)C#N | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616700
(US20230278998, Compound 18)Show SMILES CC(C)C(=O)N1CCN(CC1)c1cc(cc2c(nn(C3CCCCO3)c12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(CC1)C#N | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616727
(US20230278998, Compound 46)Show SMILES Cn1nc(-c2nnc(s2)C(F)F)c2cc(cc(N3CCC4(COC4)CC3)c12)S(=O)(=O)NC1(CC1)C#N | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616685
(US20230278998, Compound 3)Show SMILES CC(C)C(=O)N1CCN(CC1)c1cc(cc2c(n[nH]c12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(C)CC1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616694
(US20230278998, Comparative Compound 1' | US2023030...)Show SMILES CC(C)C(=O)N1CCN(CC1)c1cc(cc2n(ncc12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(CC1)C#N | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM616747
(US20230278998, Comparative Compound 2')Show SMILES FC(F)c1nnc(s1)-n1ncc2c(cc(cc12)S(=O)(=O)NC1(CC1)C#N)N1CCC2(COC2)CC1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2H70KZ8 |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 130
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 108
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371055
(US10239843, Example 162)Show SMILES Cc1ncc(Cn2c(=O)n(Cc3sc(C)nc3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(C)CC2)s1 Show InChI InChI=1S/C23H25N5O4S3/c1-13-20(34-15(3)25-13)12-27-19-6-5-17(35(31,32)26-23(4)7-8-23)9-18(19)21(29)28(22(27)30)11-16-10-24-14(2)33-16/h5-6,9-10,26H,7-8,11-12H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 38
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 40
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 36
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371355
(1-[(2,4-Dimethylthiazol-5-yl)methyl]-N-[1-(fluorom...)Show SMILES Cc1nc(C)c(Cn2c3ccc(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(CF)CC2)s1 Show InChI InChI=1S/C23H25FN6O4S2/c1-14-20(35-15(2)26-14)12-29-19-5-4-17(36(33,34)27-23(13-24)6-7-23)8-18(19)21(31)30(22(29)32)11-16-9-25-28(3)10-16/h4-5,8-10,27H,6-7,11-13H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371063
(US10239843, Example 170)Show SMILES Cc1nc(C)c(Cn2c3ccc(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(C)CC2)s1 Show InChI InChI=1S/C23H26N6O4S2/c1-14-20(34-15(2)25-14)13-28-19-6-5-17(35(32,33)26-23(3)7-8-23)9-18(19)21(30)29(22(28)31)12-16-10-24-27(4)11-16/h5-6,9-11,26H,7-8,12-13H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 131
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371463
(N-[1-(Fluoromethyl)cyclopropyl]-3-[(1-methylpyrazo...)Show SMILES Cc1ncsc1Cn1c2ccc(cc2c(=O)n(Cc2cnn(C)c2)c1=O)S(=O)(=O)NC1(CF)CC1 Show InChI InChI=1S/C22H23FN6O4S2/c1-14-19(34-13-24-14)11-28-18-4-3-16(35(32,33)26-22(12-23)5-6-22)7-17(18)20(30)29(21(28)31)10-15-8-25-27(2)9-15/h3-4,7-9,13,26H,5-6,10-12H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371294
(N-(1-Cyanocyclopropyl)-1-[(2,4-dimethylthiazol-5-y...)Show SMILES Cc1ncc(Cn2c(=O)n(Cc3sc(C)nc3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(CC2)C#N)s1 Show InChI InChI=1S/C23H22N6O4S3/c1-13-20(35-15(3)26-13)11-28-19-5-4-17(36(32,33)27-23(12-24)6-7-23)8-18(19)21(30)29(22(28)31)10-16-9-25-14(2)34-16/h4-5,8-9,27H,6-7,10-11H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371454
(N-[1-(Fluoromethyl)cyclopropyl]-3-[(1-methylpyrazo...)Show SMILES Cn1cc(Cn2c(=O)n(Cc3cncs3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)cn1 Show InChI InChI=1S/C21H21FN6O4S2/c1-26-9-14(7-24-26)10-28-19(29)17-6-16(34(31,32)25-21(12-22)4-5-21)2-3-18(17)27(20(28)30)11-15-8-23-13-33-15/h2-3,6-9,13,25H,4-5,10-12H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 37
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371470
(N-[1-(Fluoromethyl)cyclopropyl]-1-[(5-methylisoxaz...)Show SMILES Cc1oncc1Cn1c2ccc(cc2c(=O)n(Cc2cnn(C)c2)c1=O)S(=O)(=O)NC1(CF)CC1 Show InChI InChI=1S/C22H23FN6O5S/c1-14-16(9-25-34-14)12-28-19-4-3-17(35(32,33)26-22(13-23)5-6-22)7-18(19)20(30)29(21(28)31)11-15-8-24-27(2)10-15/h3-4,7-10,26H,5-6,11-13H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 46
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 12
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 9.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 28
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371469
(N-[1-(Fluoromethyl)cyclopropyl]-1-(isothiazol-5-yl...)Show SMILES Cn1cc(Cn2c(=O)n(Cc3ccns3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)cn1 Show InChI InChI=1S/C21H21FN6O4S2/c1-26-10-14(9-23-26)11-28-19(29)17-8-16(34(31,32)25-21(13-22)5-6-21)2-3-18(17)27(20(28)30)12-15-4-7-24-33-15/h2-4,7-10,25H,5-6,11-13H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 61
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371289
(1-[(2,4-Dimethylthiazol-5-yl)methyl]-7-fluoro-N-(1...)Show SMILES Cc1nc(C)c(Cn2c3cc(F)c(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(C)CC2)o1 Show InChI InChI=1S/C23H25FN6O5S/c1-13-19(35-14(2)26-13)12-29-18-8-17(24)20(36(33,34)27-23(3)5-6-23)7-16(18)21(31)30(22(29)32)11-15-9-25-28(4)10-15/h7-10,27H,5-6,11-12H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371267
(US10239843, Example 374)Show SMILES Cc1nc(C)c(Cn2c3ccc(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(CC2)C#N)o1 Show InChI InChI=1S/C23H23N7O5S/c1-14-20(35-15(2)26-14)12-29-19-5-4-17(36(33,34)27-23(13-24)6-7-23)8-18(19)21(31)30(22(29)32)11-16-9-25-28(3)10-16/h4-5,8-10,27H,6-7,11-12H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 4
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371056
(US10239843, Example 163)Show SMILES Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)n3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1 Show InChI InChI=1S/C23H26N7O4S/c1-14-9-17(28(4)26-14)13-29-20-6-5-18(35(33,34)27-23(3)7-8-23)10-19(20)21(31)30(22(29)32)12-16-11-24-15(2)25-16/h5-6,9-11,27H,7-8,12-13H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 5
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UniProtKB/SwissProt
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| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
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Citation and Details
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 45
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| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 25
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antibodypedia
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| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 89
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antibodypedia
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| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 6
| PDB
UniProtKB/SwissProt
antibodypedia
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| UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 116
| PDB
UniProtKB/SwissProt
antibodypedia
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| UniChem
| | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
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| |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 64
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| | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 10
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| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371519
(N-[1-(Fluoromethyl)cyclopropyl]-1-[(1-methylpyrazo...)Show SMILES Cc1nnc(Cn2c(=O)n(Cc3cnn(C)c3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)s1 Show InChI InChI=1S/C21H22FN7O4S2/c1-13-24-25-18(34-13)11-29-19(30)16-7-15(35(32,33)26-21(12-22)5-6-21)3-4-17(16)28(20(29)31)10-14-8-23-27(2)9-14/h3-4,7-9,26H,5-6,10-12H2,1-2H3 | PDB
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PC sid
UniChem
| US Patent
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 73
| PDB
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| UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
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| |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 90
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| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371506
(1-[(2,4-Dimethylthiazol-5-yl)methyl]-N-[1-(fluorom...)Show SMILES Cc1cc(Cn2c(=O)n(Cc3sc(C)nc3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)on1 Show InChI InChI=1S/C23H24FN5O5S2/c1-13-8-16(34-26-13)10-29-21(30)18-9-17(36(32,33)27-23(12-24)6-7-23)4-5-19(18)28(22(29)31)11-20-14(2)25-15(3)35-20/h4-5,8-9,27H,6-7,10-12H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 122
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 110
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| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
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Citation and Details
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371066
(US10239843, Example 173)Show SMILES Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1 Show InChI InChI=1S/C23H27N7O4S/c1-15-9-17(28(4)25-15)14-29-20-6-5-18(35(33,34)26-23(2)7-8-23)10-19(20)21(31)30(22(29)32)13-16-11-24-27(3)12-16/h5-6,9-12,26H,7-8,13-14H2,1-4H3 | PDB
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371049
(US10239843, Example 156)Show SMILES Cc1ncc(Cn2c(=O)n(CC3CC3)c3ccc(cc3c2=O)S(=O)(=O)NC2(C)CC2)s1 Show InChI InChI=1S/C21H24N4O4S2/c1-13-22-10-15(30-13)12-25-19(26)17-9-16(31(28,29)23-21(2)7-8-21)5-6-18(17)24(20(25)27)11-14-3-4-14/h5-6,9-10,14,23H,3-4,7-8,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | BDBM371479
(N-[1-(Fluoromethyl)cyclopropyl]-1-[(3-methylimidaz...)Show SMILES Cn1cc(Cn2c(=O)n(Cc3cncn3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)cn1 Show InChI InChI=1S/C22H24FN7O4S/c1-27-14-24-9-16(27)12-29-19-4-3-17(35(33,34)26-22(13-23)5-6-22)7-18(19)20(31)30(21(29)32)11-15-8-25-28(2)10-15/h3-4,7-10,14,26H,5-6,11-13H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanita
| Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ... |
J Med Chem 51: 1058-62 (2008)
BindingDB Entry DOI: 10.7270/Q21R6SSM |
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 57
| PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
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| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 63
| PDB
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antibodypedia
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| UniChem
| | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
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| |
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More data for this
Ligand-Target Pair | |
Poly(ADP-ribose) glycohydrolase
(Homo sapiens (Human)) | US20240083908, Example 121
| PDB
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antibodypedia
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| UniChem
| | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
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More data for this
Ligand-Target Pair | |
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