Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein phosphatase 5 [180-384] (Homo sapiens (Human)) | BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 25 | -43.4 | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Texas Wesleyan University | Assay Description For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche... | BMC Biochem 16: 19 (2015) Article DOI: 10.1186/s12858-015-0048-3 BindingDB Entry DOI: 10.7270/Q26972FW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University of Wisconsin | Assay Description This assay was done with full-length protein (containing both domains), andusing pERK as substrate. | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231697 (RR601) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University of Wisconsin | Assay Description This assay was done with full-length protein (containing both domains), andusing pERK as substrate. | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Concordia University of Wisconsin | Assay Description This assay was done with full-length protein (containing both domains), andusing pERK as substrate. | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.25E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231697 (RR601) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.45E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231697 (RR601) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.65E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231697 (RR601) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.69E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.85E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Briefly, assays without and with inhibitors were performed in Greiner 96-well clear bottom plates with a total assay volume of 200 μL. The assay... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.88E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.66E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.21E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.60E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.88E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 (Homo sapiens (Human)) | BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid | NCI2602 | RR53...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.25E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Concordia University of Wisconsin | Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio... | BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 [180-384] (Homo sapiens (Human)) | BDBM225233 (RR505 | SM1842) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10E+6 | n/a | n/a | n/a | n/a | n/a | 25 |
Texas Wesleyan University | Assay Description For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche... | BMC Biochem 16: 19 (2015) Article DOI: 10.1186/s12858-015-0048-3 BindingDB Entry DOI: 10.7270/Q26972FW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 [180-384] (Homo sapiens (Human)) | BDBM50103242 (CHEMBL316894 | Naphthalene trisulfonate (NTS) | na...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.40E+6 | n/a | n/a | n/a | n/a | n/a | 25 |
Texas Wesleyan University | Assay Description For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche... | BMC Biochem 16: 19 (2015) Article DOI: 10.1186/s12858-015-0048-3 BindingDB Entry DOI: 10.7270/Q26972FW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 [180-384] (Homo sapiens (Human)) | BDBM225235 (RR506) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+7 | n/a | n/a | n/a | n/a | n/a | 25 |
Texas Wesleyan University | Assay Description For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche... | BMC Biochem 16: 19 (2015) Article DOI: 10.1186/s12858-015-0048-3 BindingDB Entry DOI: 10.7270/Q26972FW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 5 [180-384] (Homo sapiens (Human)) | BDBM225233 (RR505 | SM1842) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+7 | n/a | n/a | n/a | n/a | n/a | 25 |
Texas Wesleyan University | Assay Description For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche... | BMC Biochem 16: 19 (2015) Article DOI: 10.1186/s12858-015-0048-3 BindingDB Entry DOI: 10.7270/Q26972FW | |||||||||||
More data for this Ligand-Target Pair |