Compile Data Set for Download or QSAR

Found 17 hits Enz. Inhib. hit(s) with Target = 'Ephrin type-A receptor 4 [29-209]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES COc1ccc2[nH]cc(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	640	-35.4	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223301 (120H10) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	960	-34.3	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223310 (123C7) Show SMILES COc1ccc2c(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c[nH]c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.59E+3	-33.1	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223305 (123C2) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccccc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.59E+3	-33.1	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223300 (EphA4-LBC inhibitor, Compound 22) Show SMILES NCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.14E+3	-32.4	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223307 (123C3) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccc(F)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.22E+3	-32.3	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223308 (123C5) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccc(O)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.57E+3	-31.9	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223302 (123B1) Show SMILES NCCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.04E+3	-31.5	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223309 (123C6) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccc(Cl)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.14E+3	-31.4	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223306 (123C12) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1cccc2ccccc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.67E+3	-29.2	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223303 (120G1) Show SMILES NCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1ccncc1)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+4	-27.7	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223304 (120G2) Show SMILES CC(C)(N)C(C)(C)C(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1ccncc1)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+5	-22.8	n/a	n/a	n/a	n/a	n/a	7.2	25
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223310 (123C7) Show SMILES COc1ccc2c(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c[nH]c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	540	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223308 (123C5) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccc(O)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223305 (123C2) Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccccc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223311 (123C4) Show SMILES COc1ccc2[nH]cc(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	420	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 [29-209] (Homo sapiens (Human))	BDBM223300 (EphA4-LBC inhibitor, Compound 22) Show SMILES NCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	6.5	27
Sanford-Burnham-Prebys Medical Discovery Institute					Assay Description The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...				Cell Chem Biol 24: 293-305 (2017) Article DOI: 10.1016/j.chembiol.2017.01.006 BindingDB Entry DOI: 10.7270/Q2GX49FB
					More data for this Ligand-Target Pair