Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1517-1688]/Mastoparan-2 [1420-1466]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1517-1688]/Mastoparan-2 [1420-1466] (West Nile virus (WNV))	BDBM33247 (benzenecarboximidamide, 1) Show SMILES NC(=N)c1cccc(NC(=O)Nc2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C15H16N6O/c16-13(17)9-3-1-5-11(7-9)20-15(22)21-12-6-2-4-10(8-12)14(18)19/h1-8H,(H3,16,17)(H3,18,19)(H2,20,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	8.5	37
University of Zurich					Assay Description Inhibitors were assayed in a 96-well plate format using enzyme conjugate WNV CF40-gly-NS3pro187, which was preincubated with various concentrations o...				J Med Chem 52: 4860-8 (2009) Article DOI: 10.1021/jm900448m BindingDB Entry DOI: 10.7270/Q20C4T4N
					More data for this Ligand-Target Pair
Genome polyprotein [1517-1688]/Mastoparan-2 [1420-1466] (West Nile virus (WNV))	BDBM33249 (4-nitrophenyl 4-carbamimidamidobenzoate, 2) Show SMILES N\C([NH-])=[NH+]\c1ccc(cc1)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H12N4O4/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21/h1-8H,(H4,15,16,17,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.42E+4	n/a	n/a	n/a	n/a	8.5	37
University of Zurich					Assay Description Inhibitors were assayed in a 96-well plate format using enzyme conjugate WNV CF40-gly-NS3pro187, which was preincubated with various concentrations o...				J Med Chem 52: 4860-8 (2009) Article DOI: 10.1021/jm900448m BindingDB Entry DOI: 10.7270/Q20C4T4N
					More data for this Ligand-Target Pair
Genome polyprotein [1517-1688]/Mastoparan-2 [1420-1466] (West Nile virus (WNV))	BDBM33247 (benzenecarboximidamide, 1) Show SMILES NC(=N)c1cccc(NC(=O)Nc2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C15H16N6O/c16-13(17)9-3-1-5-11(7-9)20-15(22)21-12-6-2-4-10(8-12)14(18)19/h1-8H,(H3,16,17)(H3,18,19)(H2,20,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	7.5	25
University of Zurich					Assay Description Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...				J Med Chem 52: 4860-8 (2009) Article DOI: 10.1021/jm900448m BindingDB Entry DOI: 10.7270/Q20C4T4N
					More data for this Ligand-Target Pair
Genome polyprotein [1517-1688]/Mastoparan-2 [1420-1466] (West Nile virus (WNV))	BDBM33249 (4-nitrophenyl 4-carbamimidamidobenzoate, 2) Show SMILES N\C([NH-])=[NH+]\c1ccc(cc1)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H12N4O4/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21/h1-8H,(H4,15,16,17,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	7.5	25
University of Zurich					Assay Description Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...				J Med Chem 52: 4860-8 (2009) Article DOI: 10.1021/jm900448m BindingDB Entry DOI: 10.7270/Q20C4T4N
					More data for this Ligand-Target Pair