Compile Data Set for Download or QSAR

Found 13 hits Enz. Inhib. hit(s) with Target = 'Dimer of Prostaglandin E2 receptor EP3 subtype'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184625 (US9156810, 44) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C(C)(C)C(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C22H36O5/c1-4-5-8-11-16(23)14-15-18-17(20(26)22(2,3)21(18)27)12-9-6-7-10-13-19(24)25/h6,9,14-18,21,23,27H,4-5,7-8,10-13H2,1-3H3,(H,24,25)/b9-6-,15-14+/t16-,17+,18+,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	4.60	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184624 (US9156810, 43) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C(C)(C)C(=O)[C@@H]1CC#CCCCC(O)=O Show InChI InChI=1S/C22H34O5/c1-4-5-8-11-16(23)14-15-18-17(20(26)22(2,3)21(18)27)12-9-6-7-10-13-19(24)25/h14-18,21,23,27H,4-5,7-8,10-13H2,1-3H3,(H,24,25)/b15-14+/t16-,17+,18+,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70E+3	n/a	11	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184631 (US9156810, (54, 55)) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)Cc2cc3ccccc3s2)[C@@H](C\C=C/CCCC(O)=O)C1=O Show InChI InChI=1S/C26H32O5S/c1-26(2)24(30)20(10-5-3-4-6-12-23(28)29)21(25(26)31)14-13-18(27)16-19-15-17-9-7-8-11-22(17)32-19/h3,5,7-9,11,13-15,18,20-21,25,27,31H,4,6,10,12,16H2,1-2H3,(H,28,29)/b5-3-,14-13+/t18?,20-,21-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184629 (US9156810, (50, 51)) Show SMILES COC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\C(O)CCc2ccccc2)[C@H](O)C(C)(C)C1=O Show InChI InChI=1S/C26H36O5/c1-26(2)24(29)21(13-9-4-5-10-14-23(28)31-3)22(25(26)30)18-17-20(27)16-15-19-11-7-6-8-12-19/h4,6-9,11-12,17-18,20-22,25,27,30H,5,10,13-16H2,1-3H3/b9-4-,18-17+/t20?,21-,22-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.61E+3	n/a	>1.00E+4	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184627 (US9156810, (46, 47) | US9156810, 46/47) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)Cc2ccccc2)[C@@H](C\C=C/CCCC(O)=O)C1=O Show InChI InChI=1S/C24H32O5/c1-24(2)22(28)19(12-8-3-4-9-13-21(26)27)20(23(24)29)15-14-18(25)16-17-10-6-5-7-11-17/h3,5-8,10-11,14-15,18-20,23,25,29H,4,9,12-13,16H2,1-2H3,(H,26,27)/b8-3-,15-14+/t18?,19-,20-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	589	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184626 (US9156810, 45) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C(C)(C)C(=O)[C@@H]1C\C=C/CCCC(=O)OC Show InChI InChI=1S/C23H38O5/c1-5-6-9-12-17(24)15-16-19-18(21(26)23(2,3)22(19)27)13-10-7-8-11-14-20(25)28-4/h7,10,15-19,22,24,27H,5-6,8-9,11-14H2,1-4H3/b10-7-,16-15+/t17-,18+,19+,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	531	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184623 (US9156810, 42) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C(C)(C)C(=O)[C@@H]1CC#CCCCC(=O)OC Show InChI InChI=1S/C23H36O5/c1-5-6-9-12-17(24)15-16-19-18(21(26)23(2,3)22(19)27)13-10-7-8-11-14-20(25)28-4/h15-19,22,24,27H,5-6,8-9,11-14H2,1-4H3/b16-15+/t17-,18+,19+,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	559	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM60734 (US9156810, 23/24) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)CCc2sc3ccccc3c2Cl)[C@@H](SCCCSCC(O)=O)C1=O Show InChI InChI=1S/C25H31ClO5S3/c1-25(2)23(30)17(22(24(25)31)33-13-5-12-32-14-20(28)29)10-8-15(27)9-11-19-21(26)16-6-3-4-7-18(16)34-19/h3-4,6-8,10,15,17,22-23,27,30H,5,9,11-14H2,1-2H3,(H,28,29)/b10-8+/t15?,17-,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184627 (US9156810, (46, 47) | US9156810, 46/47) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)Cc2ccccc2)[C@@H](C\C=C/CCCC(O)=O)C1=O Show InChI InChI=1S/C24H32O5/c1-24(2)22(28)19(12-8-3-4-9-13-21(26)27)20(23(24)29)15-14-18(25)16-17-10-6-5-7-11-17/h3,5-8,10-11,14-15,18-20,23,25,29H,4,9,12-13,16H2,1-2H3,(H,26,27)/b8-3-,15-14+/t18?,19-,20-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184636 (US9156810, (70, 71)) Show SMILES COC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\C(O)Cc2cc3ccccc3s2)[C@H](O)C(C)(C)C1=O Show InChI InChI=1S/C27H34O5S/c1-27(2)25(30)21(11-6-4-5-7-13-24(29)32-3)22(26(27)31)15-14-19(28)17-20-16-18-10-8-9-12-23(18)33-20/h4,6,8-10,12,14-16,19,21-22,26,28,31H,5,7,11,13,17H2,1-3H3/b6-4-,15-14+/t19?,21-,22-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184631 (US9156810, (54, 55)) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)Cc2cc3ccccc3s2)[C@@H](C\C=C/CCCC(O)=O)C1=O Show InChI InChI=1S/C26H32O5S/c1-26(2)24(30)20(10-5-3-4-6-12-23(28)29)21(25(26)31)14-13-18(27)16-19-15-17-9-7-8-11-22(17)32-19/h3,5,7-9,11,13-15,18,20-21,25,27,31H,4,6,10,12,16H2,1-2H3,(H,28,29)/b5-3-,14-13+/t18?,20-,21-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184630 (US9156810, (52, 53)) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)CCc2ccccc2)[C@@H](C\C=C/CCCC(O)=O)C1=O Show InChI InChI=1S/C25H34O5/c1-25(2)23(29)20(12-8-3-4-9-13-22(27)28)21(24(25)30)17-16-19(26)15-14-18-10-6-5-7-11-18/h3,5-8,10-11,16-17,19-21,24,26,30H,4,9,12-15H2,1-2H3,(H,27,28)/b8-3-,17-16+/t19?,20-,21-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	60	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair
Dimer of Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM184630 (US9156810, (52, 53)) Show SMILES CC1(C)[C@@H](O)[C@H](\C=C\C(O)CCc2ccccc2)[C@@H](C\C=C/CCCC(O)=O)C1=O Show InChI InChI=1S/C25H34O5/c1-25(2)23(29)20(12-8-3-4-9-13-22(27)28)21(24(25)30)17-16-19(26)15-14-18-10-6-5-7-11-18/h3,5-8,10-11,16-17,19-21,24,26,30H,4,9,12-15H2,1-2H3,(H,27,28)/b8-3-,17-16+/t19?,20-,21-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	7.4	4
Allergan, Inc. US Patent					Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...				US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K
					More data for this Ligand-Target Pair