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Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with Target = 'Falcilysin'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552265
PNG
(CHEMBL4799253)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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UniChem
Article
PubMed
 220n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552271
PNG
(CHEMBL4743280)
Show SMILES COC(=O)C1CN(CCN1S(=O)(=O)c1ccc(\C=C\c2ccccc2)cc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

GoogleScholar
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UniChem
Article
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 600n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552264
PNG
(CHEMBL4782486)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1cccc(c1)-c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

GoogleScholar
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PC sid
UniChem
Article
PubMed
 900n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552268
PNG
(CHEMBL4799260)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1cccc(\C=C\c2ccccc2)c1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
 1.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552275
PNG
(CHEMBL4797916)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(\C=C\c2ccccc2)cc1
PDB

UniProtKB/TrEMBL

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PC sid
UniChem
Article
PubMed
 1.10E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552272
PNG
(CHEMBL4794156)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1cccc(Br)c1
PDB

UniProtKB/TrEMBL

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UniChem
Article
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 1.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552263
PNG
(CHEMBL4749474)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1cccc(Br)c1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

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 1.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552269
PNG
(CHEMBL4785958)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1cccc(c1)-c1ccc(cc1)C(=O)c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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Article
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 1.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552266
PNG
(CHEMBL4753948)
Show SMILES COC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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Article
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 2.50E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552270
PNG
(CHEMBL4741390)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1cccc(CCc2ccccc2)c1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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UniChem
Article
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 2.50E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552273
PNG
(CHEMBL4763576)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(I)cc1
PDB

UniProtKB/TrEMBL

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Article
PubMed
 2.60E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461717
PNG
(CHEMBL4225532)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H22BrN3O5S/c25-20-10-12-21(13-11-20)34(32,33)28-15-14-27(16-22(28)23(29)26-31)24(30)19-8-6-18(7-9-19)17-4-2-1-3-5-17/h1-13,22,31H,14-16H2,(H,26,29)
PDB

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Article
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 3.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552258
PNG
(CHEMBL4759772)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1ccc2ccccc2c1
PDB

UniProtKB/TrEMBL

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UniChem
Article
PubMed
 3.50E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552261
PNG
(CHEMBL4797275)
Show SMILES COC(=O)C1CN(Cc2ccc(cc2)-c2ccccc2)CCN1S(=O)(=O)c1ccc(Br)cc1
PDB

UniProtKB/TrEMBL

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UniChem
Article
PubMed
 4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552267
PNG
(CHEMBL4749198)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1cccc(c1)-c1cccnc1OC)S(=O)(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
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Article
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 4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552274
PNG
(CHEMBL4747594)
Show SMILES CNC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1cccnc1OC
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
 4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552252
PNG
(CHEMBL4787612)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(I)cc1)C(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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Article
PubMed
 4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552262
PNG
(CHEMBL4746210)
Show SMILES ONC(=O)C1CN(Cc2ccc(cc2)-c2ccccc2)CCN1S(=O)(=O)c1ccc(I)cc1
PDB

UniProtKB/TrEMBL

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Article
PubMed
 4.90E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552260
PNG
(CHEMBL4786923)
Show SMILES ONC(=O)C1CN(Cc2ccc(cc2)-c2ccccc2)CCN1S(=O)(=O)c1ccc(Br)cc1
PDB

UniProtKB/TrEMBL

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Article
PubMed
 5.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552257
PNG
(CHEMBL4744749)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1cccc2ccccc12
PDB

UniProtKB/TrEMBL

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Article
PubMed
 9.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552253
PNG
(CHEMBL4748768)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
 1.00E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552254
PNG
(CHEMBL4760331)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)-c1ccsc1)C(=O)c1ccc(cc1)-c1ccccc1
PDB

UniProtKB/TrEMBL

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UniChem
Article
PubMed
 1.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552276
PNG
(CHEMBL4779972)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)S(=O)(=O)c1ccc(Cc2ccccc2)cc1
PDB

UniProtKB/TrEMBL

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PC cid
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UniChem
Article
PubMed
>2.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552277
PNG
(CHEMBL4795927)
Show SMILES ONC(=O)C1CNCCN1S(=O)(=O)c1ccc(cc1)C#C
PDB

UniProtKB/TrEMBL

GoogleScholar
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PC cid
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Article
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>2.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552259
PNG
(CHEMBL4793336)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)C#C)C(=O)c1ccc(cc1)C(=O)c1ccccc1
PDB

UniProtKB/TrEMBL

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PC cid
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Article
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>2.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552256
PNG
(CHEMBL4743581)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(cc1)C#C)C(=O)c1ccc(I)cc1
PDB

UniProtKB/TrEMBL

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Article
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>2.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50552255
PNG
(CHEMBL4783383)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1ccc(I)cc1
PDB

UniProtKB/TrEMBL

GoogleScholar
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PC cid
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Article
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>2.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Plasmodium falciparum FLN

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127683
BindingDB Entry DOI: 10.7270/Q25B064W
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461717
PNG
(CHEMBL4225532)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H22BrN3O5S/c25-20-10-12-21(13-11-20)34(32,33)28-15-14-27(16-22(28)23(29)26-31)24(30)19-8-6-18(7-9-19)17-4-2-1-3-5-17/h1-13,22,31H,14-16H2,(H,26,29)
PDB

UniProtKB/TrEMBL

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Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461722
PNG
(CHEMBL4226440)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C18H17Cl2N3O5S/c19-14-7-6-12(10-15(14)20)18(25)22-8-9-23(16(11-22)17(24)21-26)29(27,28)13-4-2-1-3-5-13/h1-7,10,16,26H,8-9,11H2,(H,21,24)
PDB

UniProtKB/TrEMBL

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UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461726
PNG
(CHEMBL4228497)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H19Cl2N3O6S/c1-30-13-3-5-14(6-4-13)31(28,29)24-9-8-23(11-17(24)18(25)22-27)19(26)12-2-7-15(20)16(21)10-12/h2-7,10,17,27H,8-9,11H2,1H3,(H,22,25)
PDB

UniProtKB/TrEMBL

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Article
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n/an/a 6.00E+3n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461718
PNG
(CHEMBL4227329)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1ccccc1Br
Show InChI InChI=1S/C18H18BrN3O5S/c19-15-9-5-4-8-14(15)18(24)21-10-11-22(16(12-21)17(23)20-25)28(26,27)13-6-2-1-3-7-13/h1-9,16,25H,10-12H2,(H,20,23)
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n/an/a 7.00E+3n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461723
PNG
(CHEMBL4227286)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C24H23N3O5S/c28-23(25-30)22-17-26(15-16-27(22)33(31,32)21-9-5-2-6-10-21)24(29)20-13-11-19(12-14-20)18-7-3-1-4-8-18/h1-14,22,30H,15-17H2,(H,25,28)
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n/an/a 8.00E+3n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461724
PNG
(CHEMBL4228556)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccccc1Br
Show InChI InChI=1S/C19H20BrN3O6S/c1-29-13-6-8-14(9-7-13)30(27,28)23-11-10-22(12-17(23)18(24)21-26)19(25)15-4-2-3-5-16(15)20/h2-9,17,26H,10-12H2,1H3,(H,21,24)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461715
PNG
(CHEMBL4227719)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1cccc(Br)c1
Show InChI InChI=1S/C19H20BrN3O6S/c1-29-15-5-7-16(8-6-15)30(27,28)23-10-9-22(12-17(23)18(24)21-26)19(25)13-3-2-4-14(20)11-13/h2-8,11,17,26H,9-10,12H2,1H3,(H,21,24)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50084726
PNG
(4-(Biphenyl-4-carbonyl)-1-(4-methoxy-benzenesulfon...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C25H25N3O6S/c1-34-21-11-13-22(14-12-21)35(32,33)28-16-15-27(17-23(28)24(29)26-31)25(30)20-9-7-19(8-10-20)18-5-3-2-4-6-18/h2-14,23,31H,15-17H2,1H3,(H,26,29)
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n/an/a 1.00E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461716
PNG
(CHEMBL4227787)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C18H18BrN3O5S/c19-14-8-6-13(7-9-14)18(24)21-10-11-22(16(12-21)17(23)20-25)28(26,27)15-4-2-1-3-5-15/h1-9,16,25H,10-12H2,(H,20,23)
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n/an/a 1.30E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461725
PNG
(CHEMBL4224730)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C19H20BrN3O6S/c1-29-15-6-8-16(9-7-15)30(27,28)23-11-10-22(12-17(23)18(24)21-26)19(25)13-2-4-14(20)5-3-13/h2-9,17,26H,10-12H2,1H3,(H,21,24)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461730
PNG
(CHEMBL4225559)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C18H17BrFN3O5S/c19-13-3-7-15(8-4-13)29(27,28)23-10-9-22(11-16(23)17(24)21-26)18(25)12-1-5-14(20)6-2-12/h1-8,16,26H,9-11H2,(H,21,24)
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n/an/a 1.60E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461720
PNG
(CHEMBL4225657)
Show SMILES CCCCN1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H23N3O4S/c1-2-3-9-17-10-11-18(14(12-17)15(19)16-20)23(21,22)13-7-5-4-6-8-13/h4-8,14,20H,2-3,9-12H2,1H3,(H,16,19)
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n/an/a 3.00E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461733
PNG
(CHEMBL4229016)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1cccc(F)c1
Show InChI InChI=1S/C18H17BrFN3O5S/c19-13-4-6-15(7-5-13)29(27,28)23-9-8-22(11-16(23)17(24)21-26)18(25)12-2-1-3-14(20)10-12/h1-7,10,16,26H,8-9,11H2,(H,21,24)
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n/an/a 3.10E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461728
PNG
(CHEMBL4225259)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H18BrN3O5S/c19-14-6-8-15(9-7-14)28(26,27)22-11-10-21(12-16(22)17(23)20-25)18(24)13-4-2-1-3-5-13/h1-9,16,25H,10-12H2,(H,20,23)
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n/an/a 3.50E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461721
PNG
(CHEMBL4226498)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H19N3O5S/c22-17(19-24)16-13-20(18(23)14-7-3-1-4-8-14)11-12-21(16)27(25,26)15-9-5-2-6-10-15/h1-10,16,24H,11-13H2,(H,19,22)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461732
PNG
(CHEMBL4228814)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H21N3O7S2/c1-28-14-7-9-16(10-8-14)30(26,27)21-12-11-20(13-17(21)18(22)19-23)29(24,25)15-5-3-2-4-6-15/h2-10,17,23H,11-13H2,1H3,(H,19,22)
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n/an/a>5.00E+4n/an/an/an/an/an/a



California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461731
PNG
(CHEMBL4225755)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1cccc(F)c1
Show InChI InChI=1S/C18H18FN3O5S/c19-14-6-4-5-13(11-14)18(24)21-9-10-22(16(12-21)17(23)20-25)28(26,27)15-7-2-1-3-8-15/h1-8,11,16,25H,9-10,12H2,(H,20,23)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50084737
PNG
(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccccc1
Show InChI InChI=1S/C19H21N3O6S/c1-28-15-7-9-16(10-8-15)29(26,27)22-12-11-21(13-17(22)18(23)20-25)19(24)14-5-3-2-4-6-14/h2-10,17,25H,11-13H2,1H3,(H,20,23)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461727
PNG
(CHEMBL4228238)
Show SMILES CCC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C14H18BrN3O5S/c1-2-13(19)17-7-8-18(12(9-17)14(20)16-21)24(22,23)11-5-3-10(15)4-6-11/h3-6,12,21H,2,7-9H2,1H3,(H,16,20)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461729
PNG
(CHEMBL4225711)
Show SMILES ONC(=O)C1CN(CCN1S(=O)(=O)c1ccccc1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C18H18FN3O5S/c19-14-8-6-13(7-9-14)18(24)21-10-11-22(16(12-21)17(23)20-25)28(26,27)15-4-2-1-3-5-15/h1-9,16,25H,10-12H2,(H,20,23)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair
Falcilysin


(Plasmodium falciparum (isolate 3D7))		BDBM50461719
PNG
(CHEMBL4226235)
Show SMILES OCCCN1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H21N3O5S/c18-10-4-7-16-8-9-17(13(11-16)14(19)15-20)23(21,22)12-5-2-1-3-6-12/h1-3,5-6,13,18,20H,4,7-11H2,(H,15,19)
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California State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...

Bioorg Med Chem Lett 28: 1846-1848 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.010
BindingDB Entry DOI: 10.7270/Q2V69N7V
More data for this
Ligand-Target Pair