Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium/calmodulin-dependent protein kinase kinase 2 [ P274E] (Homo sapiens (Human)) | BDBM92455 (CHEMBL265470 | STO-609) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 2.42E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
RIKEN Systems and Structural Biology Center | Assay Description The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio... | J Biol Chem 286: 22570-9 (2011) Article DOI: 10.1074/jbc.M111.251710 BindingDB Entry DOI: 10.7270/Q2445K3H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |