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Compile Data Set for Download or QSAR

Found 848 hits Enz. Inhib. hit(s) with Target = 'DNA damage-binding protein 1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM511610
PNG
(US11059801, Compound dBET18)
Show SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCN1CCN(CC1)C(=O)CCCCCNC(=O)COc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(Cl)cc1 |r,c:8|
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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 1.57n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM50544938
PNG
(CHEMBL4094346 | US11059801, Compound dBET1)
Show SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCNC(=O)COc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(Cl)cc1 |r,c:8|
Show InChI InChI=1S/C38H37ClN8O7S/c1-19-20(2)55-38-31(19)33(22-9-11-23(39)12-10-22)42-25(34-45-44-21(3)46(34)38)17-29(49)40-15-4-5-16-41-30(50)18-54-27-8-6-7-24-32(27)37(53)47(36(24)52)26-13-14-28(48)43-35(26)51/h6-12,25-26H,4-5,13-18H2,1-3H3,(H,40,49)(H,41,50)(H,43,48,51)/t25-,26?/m0/s1
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UniProtKB/SwissProt

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MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 3.09n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM511611
PNG
(US11059801, Compound dBET19)
Show SMILES Cc1nnc2[C@H](CC(=O)NCCCCNC(=O)COc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)N=C(c3c(C)c(CC#N)sc3-n12)c1ccc(Cl)cc1 |r,c:41|
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UniProtKB/SwissProt

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US Patent
n/an/a 3.62n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM511608
PNG
(US11059801, Compound dBET16)
Show SMILES COc1cc(ccc1Nc1ccc2N(C)C(=O)[C@@H](C)N(C3CCCC3)c2n1)C(=O)NCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 |r|
PDB

UniProtKB/SwissProt

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n/an/a 4.84n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM511621
PNG
(US11059801, Compound dBET29)
Show SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCCCOc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(Cl)cc1 |r,c:8|
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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 6.05n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM511609
PNG
(US11059801, Compound dBET17)
Show SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCNC(=O)COc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(cc1)C#N |r,c:8|
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 6.41n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM511594
PNG
(US11059801, Compound dBET2)
Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NCCCCNC(=O)COc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)ncc2N(C)C1=O |r|
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UniProtKB/SwissProt

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US Patent
n/an/a 7.30n/an/an/an/an/an/a


TBA

Assay Description
A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2G44TFM
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547722
PNG
(US11292792, CMPD # I-52)
Show SMILES O=C1CCC(C(=O)N1)n1c2cccc(C#CCOCCOCCOCc3ccccc3)c2c2cccnc12
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547727
PNG
(US11292792, CMPD # I-57)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCCCc1ccnc2n(C3CCC(=O)NC3=O)c3ccccc3c12
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547729
PNG
(US11292792, CMPD # I-59)
Show SMILES NCCOCCOCCCc1cnc2n(C3CCC(=O)NC3=O)c3ccccc3c2c1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547730
PNG
(US11292792, CMPD # I-60)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCCCc1cccc2n(C3CCC(=O)NC3=O)c3ncccc3c12
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UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547731
PNG
(US11292792, CMPD # I-61)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCC#Cc1cccc2n(C3CCC(=O)NC3=O)c3ncccc3c12
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547732
PNG
(US11292792, CMPD # I-62)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCCCc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
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UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547733
PNG
(US11292792, CMPD # I-63)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCC#Cc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547734
PNG
(US11292792, CMPD # I-64)
Show SMILES CC(C)(C)OC(=O)N1CCN(CCc2ccc3n(C4CCC(=O)NC4=O)c4ncccc4c3c2)CC1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547741
PNG
(US11292792, CMPD # I-71)
Show SMILES CC(C)(C)OC(=O)NC1CCN(CCc2ccc3n(C4CCC(=O)NC4=O)c4ncccc4c3c2)CC1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547742
PNG
(US11292792, CMPD # I-72)
Show SMILES O=C1CCC(C(=O)N1)n1c2ccccc2c2ccsc12
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547745
PNG
(US11292792, CMPD # I-75)
Show SMILES Clc1ccc2c(n1)n(C1CCC(=O)NC1=O)c1ccccc21
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547746
PNG
(US11292792, CMPD # I-76)
Show SMILES O=C1CCC(C(=O)N1)n1c2ccccc2c2c(ccnc12)C#N
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547747
PNG
(US11292792, CMPD # I-77)
Show SMILES Cc1ccnc2n(C3CCC(=O)NC3=O)c3ccccc3c12
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547748
PNG
(US11292792, CMPD # I-78)
Show SMILES Nc1ccc2c(n1)n(C1CCC(=O)NC1=O)c1ccccc21
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547749
PNG
(US11292792, CMPD # I-79)
Show SMILES CNc1ccc2c3ccccc3n(C3CCC(=O)NC3=O)c2n1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547753
PNG
(US11292792, CMPD # I-83)
Show SMILES Oc1ccc2c(n1)n(C1CCC(=O)NC1=O)c1ccccc21
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547754
PNG
(US11292792, CMPD # I-84)
Show SMILES Fc1ccc2c(n1)n(C1CCC(=O)NC1=O)c1ccccc21
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547756
PNG
(US11292792, CMPD # I-86)
Show SMILES Cc1ccc2c(n1)n(C1CCC(=O)NC1=O)c1ccccc21
PDB

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TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547757
PNG
(US11292792, CMPD # I-87)
Show SMILES O=C1CCC(C(=O)N1)n1c2ccccc2c2ncsc12
PDB

UniProtKB/SwissProt

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PC sid
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547758
PNG
(US11292792, CMPD # I-88)
Show SMILES Brc1ccc2n(C3CCC(=O)NC3=O)c3sccc3c2c1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547759
PNG
(US11292792, CMPD # I-89)
Show SMILES Brc1csc2n(C3CCC(=O)NC3=O)c3ccccc3c12
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
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US Patent
n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547762
PNG
(US11292792, CMPD # I-92)
Show SMILES Fc1ccc2c3cc(Br)ccc3n(C3CCC(=O)NC3=O)c2n1
PDB

UniProtKB/SwissProt

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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547763
PNG
(US11292792, CMPD # I-93)
Show SMILES Clc1csc2n(C3CCC(=O)NC3=O)c3ccccc3c12
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547766
PNG
(US11292792, CMPD # I-100)
Show SMILES Fc1cccc2n(C3CCC(=O)NC3=O)c3ncccc3c12
PDB

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Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547767
PNG
(US11292792, CMPD # I-101)
Show SMILES Fc1ccc2c(c1)n(C1CCC(=O)NC1=O)c1ncccc21
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547769
PNG
(US11292792, CMPD # I-103)
Show SMILES Brc1cccc2n(C3CCC(=O)NC3=O)c3sccc3c12
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547691
PNG
(US11292792, CMPD # I-2)
Show SMILES O=C1CCC(C(=O)N1)n1c2ccccc2c2cccnc12
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547693
PNG
(US11292792, CMPD # I-5)
Show SMILES Nc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547694
PNG
(US11292792, CMPD # I-8)
Show SMILES CC(=O)Nc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547695
PNG
(US11292792, CMPD # I-9)
Show SMILES CCNC(=O)Nc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547696
PNG
(US11292792, CMPD # I-26)
Show SMILES Brc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547697
PNG
(US11292792, CMPD # I-27)
Show SMILES CNc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547698
PNG
(US11292792, CMPD # I-28)
Show SMILES CN(C)c1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547700
PNG
(US11292792, CMPD # I-30)
Show SMILES Brc1cccc2n(C3CCC(=O)NC3=O)c3ncccc3c12
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547701
PNG
(US11292792, CMPD # I-31)
Show SMILES Brc1ccnc2n(C3CCC(=O)NC3=O)c3ccccc3c12
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547703
PNG
(US11292792, CMPD # I-33)
Show SMILES CC(C)(C)OC(=O)NCCOCC#Cc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547704
PNG
(US11292792, CMPD # I-34)
Show SMILES CC(C)(C)OC(=O)NCCOCCCc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547705
PNG
(US11292792, CMPD # I-35)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCCNc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547706
PNG
(US11292792, CMPD # I-36)
Show SMILES CC(C)(C)OC(=O)NCCOCCOCC(=O)NCc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547708
PNG
(US11292792, CMPD # I-38)
Show SMILES CC(C)(C)OC(=O)NCCOCCOC(=O)NCc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547709
PNG
(US11292792, CMPD # I-39)
Show SMILES Nc1cnc2n(C3CCC(=O)NC3=O)c3ccccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547714
PNG
(US11292792, CMPD # I-44)
Show SMILES CN(CCCOCCCc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1)C(=O)OC(C)(C)C
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM547716
PNG
(US11292792, CMPD # I-46)
Show SMILES OCCOCCOCCCc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1
PDB

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Assay Description
Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2GQ71ZT
More data for this
Ligand-Target Pair
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