Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor [281-332]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor [281-332] (Homo sapiens (Human))	BDBM232947 (US9353067, R-55) Show SMILES Oc1cccc(c1)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1 Show InChI InChI=1S/C19H20N4O2/c24-15-5-3-4-14(12-15)23-10-8-22(9-11-23)13-18-20-17-7-2-1-6-16(17)19(25)21-18/h1-7,12,24H,8-11,13H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	7.4	22
ATIR Holding S.A. US Patent					Assay Description Determination of binding to D4.4 receptor was performed using [3H]-YM-09151-2 (70-87 Ci/mmol, 0.3 nM), as a radioligand, in the presence of various c...				US Patent US9353067 (2016) BindingDB Entry DOI: 10.7270/Q28G8JMN
					More data for this Ligand-Target Pair
D(4) dopamine receptor [281-332] (Homo sapiens (Human))	BDBM232949 (US9353067, L-238) Show SMILES Oc1ccccc1N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1 Show InChI InChI=1S/C19H20N4O2/c24-17-8-4-3-7-16(17)23-11-9-22(10-12-23)13-18-20-15-6-2-1-5-14(15)19(25)21-18/h1-8,24H,9-13H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	22
ATIR Holding S.A. US Patent					Assay Description Determination of binding to D4.4 receptor was performed using [3H]-YM-09151-2 (70-87 Ci/mmol, 0.3 nM), as a radioligand, in the presence of various c...				US Patent US9353067 (2016) BindingDB Entry DOI: 10.7270/Q28G8JMN
					More data for this Ligand-Target Pair
D(4) dopamine receptor [281-332] (Homo sapiens (Human))	BDBM232948 (US9353067, L-221) Show SMILES Oc1ccc(cc1)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1 Show InChI InChI=1S/C19H20N4O2/c24-15-7-5-14(6-8-15)23-11-9-22(10-12-23)13-18-20-17-4-2-1-3-16(17)19(25)21-18/h1-8,24H,9-13H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	7.4	22
ATIR Holding S.A. US Patent					Assay Description Determination of binding to D4.4 receptor was performed using [3H]-YM-09151-2 (70-87 Ci/mmol, 0.3 nM), as a radioligand, in the presence of various c...				US Patent US9353067 (2016) BindingDB Entry DOI: 10.7270/Q28G8JMN
					More data for this Ligand-Target Pair