Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eyes absent homolog 3 [223-510] (Homo sapiens (Human)) | BDBM18964 (4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenol | L ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Mus musculus (Mouse)) | BDBM18964 (4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenol | L ...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GNF | Assay Description The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut... | Bioorg Med Chem Lett 16: 5488-92 (2006) BindingDB Entry DOI: 10.7270/Q2ZK5JZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Mus musculus (Mouse)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GNF | Assay Description The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut... | Bioorg Med Chem Lett 16: 5488-92 (2006) BindingDB Entry DOI: 10.7270/Q2ZK5JZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Homo sapiens (Human)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Mus musculus (Mouse)) | BDBM50342278 ((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GNF | Assay Description The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut... | Bioorg Med Chem Lett 16: 5488-92 (2006) BindingDB Entry DOI: 10.7270/Q2ZK5JZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eyes absent homolog 3 [223-510] (Homo sapiens (Human)) | BDBM50342278 ((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHILDREN HOSPITAL MEDICAL CENTER US Patent | Assay Description An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003)).... | US Patent US9725430 (2017) BindingDB Entry DOI: 10.7270/Q23F4RSZ | |||||||||||
More data for this Ligand-Target Pair |