BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase haspin [465-798]'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase haspin [465-798] (Homo sapiens (Human))	BDBM103302 (SCH772984 \| US8546404, 6) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University					Assay Description The IC50 values of selected kinases were determined using either Z'LYTE, Adapta or LanthaScreen assays.				Nat Chem Biol 10: 853-860 (2014) Article DOI: 10.1038/nchembio.1629 BindingDB Entry DOI: 10.7270/Q28G8JCH
George Washington University					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin [465-798] (Homo sapiens (Human))	BDBM103302 (SCH772984 \| US8546404, 6) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	297	n/a	n/a	n/a	7.5	15
George Washington University					Assay Description For ERK1 and ERK2, the buffer contained 20 mM HEPES (pH 7.5), 150 mM NaCl and 0.5 mM TCEP. For haspin, the buffer contained 20 mM HEPES (pH 7.5), 250...				Nat Chem Biol 10: 853-860 (2014) Article DOI: 10.1038/nchembio.1629 BindingDB Entry DOI: 10.7270/Q28G8JCH
George Washington University					More data for this Ligand-Target Pair