Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin reductase 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin reductase 1 (Rattus norvegicus)	BDBM50410835 (IROFULVEN) Show SMILES CC1=C(CO)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1 |r,c:1,5,18| Show InChI InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Cytotoxicity against HEK293 cells transfected with recombinant AOR by MTT assay				J Med Chem 49: 2593-9 (2006) Article DOI: 10.1021/jm051104t BindingDB Entry DOI: 10.7270/Q2DB832Z
					More data for this Ligand-Target Pair
Prostaglandin reductase 1 (Rattus norvegicus)	BDBM50410833 (ACYLFULVENE) Show SMILES CC1=CC2=C(C)[C@]3(CC3)[C@@](C)(O)C(=O)C2=C1 |r,c:3,16,t:1| Show InChI InChI=1S/C14H16O2/c1-8-6-10-9(2)14(4-5-14)13(3,16)12(15)11(10)7-8/h6-7,16H,4-5H2,1-3H3/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Cytotoxicity against HEK293 cells transfected with recombinant AOR by MTT assay				J Med Chem 49: 2593-9 (2006) Article DOI: 10.1021/jm051104t BindingDB Entry DOI: 10.7270/Q2DB832Z
					More data for this Ligand-Target Pair
Prostaglandin reductase 1 (Rattus norvegicus)	BDBM50410834 (CHEMBL380919) Show SMILES CC1=C(CO)C2=C(C)C3(CC3)[C@](C)(O)C(=O)C2=C1 |c:1,5,18| Show InChI InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Cytotoxicity against HEK293 cells transfected with recombinant AOR by MTT assay				J Med Chem 49: 2593-9 (2006) Article DOI: 10.1021/jm051104t BindingDB Entry DOI: 10.7270/Q2DB832Z
					More data for this Ligand-Target Pair
Prostaglandin reductase 1 (Rattus norvegicus)	BDBM50410832 (CHEMBL205439) Show SMILES CC1=CC2=C(C)C3(CC3)[C@](C)(O)C(=O)C2=C1 |c:3,16,t:1| Show InChI InChI=1S/C14H16O2/c1-8-6-10-9(2)14(4-5-14)13(3,16)12(15)11(10)7-8/h6-7,16H,4-5H2,1-3H3/t13-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Cytotoxicity against HEK293 cells transfected with recombinant AOR by MTT assay				J Med Chem 49: 2593-9 (2006) Article DOI: 10.1021/jm051104t BindingDB Entry DOI: 10.7270/Q2DB832Z
					More data for this Ligand-Target Pair