Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176599 (US9120761, 13) Show SMILES CN1CCC(CC1)c1ccc(Nc2ncc(c(CCc3ccccc3CC(N)=O)n2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C27H29F4N5O/c1-36-12-10-18(11-13-36)20-7-9-24(22(28)14-20)35-26-33-16-21(27(29,30)31)23(34-26)8-6-17-4-2-3-5-19(17)15-25(32)37/h2-5,7,9,14,16,18H,6,8,10-13,15H2,1H3,(H2,32,37)(H,33,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	205	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176589 (US9120761, 3) Show SMILES COc1cc(ccc1Nc1ncc(c(CCc2ccccc2CC(N)=O)n1)C(F)(F)F)C1CCN(C)CC1 Show InChI InChI=1S/C28H32F3N5O2/c1-36-13-11-19(12-14-36)21-8-10-24(25(15-21)38-2)35-27-33-17-22(28(29,30)31)23(34-27)9-7-18-5-3-4-6-20(18)16-26(32)37/h3-6,8,10,15,17,19H,7,9,11-14,16H2,1-2H3,(H2,32,37)(H,33,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	538	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176595 (US9120761, 9) Show SMILES CCc1cc(ccc1Nc1ncc(c(CCc2ccccc2CC(N)=O)n1)C(F)(F)F)C1CCN(C)CC1 Show InChI InChI=1S/C29H34F3N5O/c1-3-19-16-23(21-12-14-37(2)15-13-21)9-10-25(19)35-28-34-18-24(29(30,31)32)26(36-28)11-8-20-6-4-5-7-22(20)17-27(33)38/h4-7,9-10,16,18,21H,3,8,11-15,17H2,1-2H3,(H2,33,38)(H,34,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176594 (US9120761, 8) Show SMILES CCc1cc(ccc1Nc1ncc(c(CCc2ccccc2CC(N)=O)n1)C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C28H32F3N5O/c1-2-18-15-22(20-11-13-33-14-12-20)8-9-24(18)35-27-34-17-23(28(29,30)31)25(36-27)10-7-19-5-3-4-6-21(19)16-26(32)37/h3-6,8-9,15,17,20,33H,2,7,10-14,16H2,1H3,(H2,32,37)(H,34,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176592 (US9120761, 6) Show SMILES COc1cc(ccc1Nc1ncc(c(CCc2cccc(c2)C(N)=O)n1)C(F)(F)F)C1CCN(C)CC1 Show InChI InChI=1S/C27H30F3N5O2/c1-35-12-10-18(11-13-35)19-7-9-23(24(15-19)37-2)34-26-32-16-21(27(28,29)30)22(33-26)8-6-17-4-3-5-20(14-17)25(31)36/h3-5,7,9,14-16,18H,6,8,10-13H2,1-2H3,(H2,31,36)(H,32,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176597 (US9120761, 11) Show SMILES CN1CCC(CC1)c1ccc(Nc2ncc(c(CCc3ccccc3CC(N)=O)n2)C(F)(F)F)c(OC(F)(F)F)c1 Show InChI InChI=1S/C28H29F6N5O2/c1-39-12-10-18(11-13-39)20-7-9-23(24(14-20)41-28(32,33)34)38-26-36-16-21(27(29,30)31)22(37-26)8-6-17-4-2-3-5-19(17)15-25(35)40/h2-5,7,9,14,16,18H,6,8,10-13,15H2,1H3,(H2,35,40)(H,36,37,38)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.98E+4	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Isoform 2 of Vascular endothelial growth factor receptor 3 (Short) 98-1298] (Homo sapiens (Human))	BDBM176596 (US9120761, 10) Show SMILES NC(=O)Cc1ccccc1CCc1nc(Nc2ccc(cc2OC(F)(F)F)C2CCNCC2)ncc1C(F)(F)F Show InChI InChI=1S/C27H27F6N5O2/c28-26(29,30)20-15-36-25(37-21(20)7-5-16-3-1-2-4-18(16)14-24(34)39)38-22-8-6-19(17-9-11-35-12-10-17)13-23(22)40-27(31,32)33/h1-4,6,8,13,15,17,35H,5,7,9-12,14H2,(H2,34,39)(H,36,37,38)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>6.60E+4	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair