Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase WNK4 [1-444] (Homo sapiens (Human)) | BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 187 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Novartis Institutes for BioMedical Research, Inc. | Assay Description The assay utilized 5 to 10 nM of WNK1−4 protein compared to 25 nM used for mobility shift assay, enabling a more accurate comparison of selecti... | ACS Chem Biol 11: 3338-3346 (2016) Article DOI: 10.1021/acschembio.6b00511 BindingDB Entry DOI: 10.7270/Q2FB51SQ | |||||||||||
More data for this Ligand-Target Pair |