Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-isopropylmalate dehydrogenase' AND taxid = 300852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-isopropylmalate dehydrogenase (Thermus thermophilus)	BDBM50481232 (CHEMBL602786) Show SMILES [Na;v0+].[Na;v0+].[H][C@]([#8])([#6](-[#8-])=O)[C@]([H])([#16]-[#6])[#6](-[#8-])=O |r| Show InChI InChI=1S/C5H8O5S.2Na/c1-11-3(5(9)10)2(6)4(7)8;;/h2-3,6H,1H3,(H,7,8)(H,9,10);;/q;2*+1/p-2/t2-,3+;;/m1../s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Institute of Technology Curated by ChEMBL					Assay Description Inhibition of Thermus thermophilus HB8 IPMDH assessed as formation of NADH by Lineweaver-Burke plot analysis				Bioorg Med Chem 17: 7789-94 (2009) Article DOI: 10.1016/j.bmc.2009.09.025 BindingDB Entry DOI: 10.7270/Q2377CHW
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