Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'Beta-lactamase' AND taxid = 654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (Aeromonas veronii)	BDBM50089390 (CHEMBL3577963) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2nc3ccccc3s2)[nH]1 Show InChI InChI=1S/C18H13N5O3S2/c24-14(20-17-19-12-7-3-4-8-13(12)28-17)9-27-18-21-15(22-23-18)10-5-1-2-6-11(10)16(25)26/h1-8H,9H2,(H,25,26)(H,19,20,24)(H,21,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089391 (CHEMBL3577964) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccc(Cl)cc2)[nH]1 Show InChI InChI=1S/C17H13ClN4O3S/c18-10-5-7-11(8-6-10)19-14(23)9-26-17-20-15(21-22-17)12-3-1-2-4-13(12)16(24)25/h1-8H,9H2,(H,19,23)(H,24,25)(H,20,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089388 (CHEMBL3577961) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccccc2)[nH]1 Show InChI InChI=1S/C17H14N4O3S/c22-14(18-11-6-2-1-3-7-11)10-25-17-19-15(20-21-17)12-8-4-5-9-13(12)16(23)24/h1-9H,10H2,(H,18,22)(H,23,24)(H,19,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089393 (CHEMBL3577970) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2cccc(c2)[N+]([O-])=O)[nH]1 Show InChI InChI=1S/C17H13N5O5S/c23-14(18-10-4-3-5-11(8-10)22(26)27)9-28-17-19-15(20-21-17)12-6-1-2-7-13(12)16(24)25/h1-8H,9H2,(H,18,23)(H,24,25)(H,19,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089392 (CHEMBL3577965) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccc(cc2)[N+]([O-])=O)[nH]1 Show InChI InChI=1S/C17H13N5O5S/c23-14(18-10-5-7-11(8-6-10)22(26)27)9-28-17-19-15(20-21-17)12-3-1-2-4-13(12)16(24)25/h1-8H,9H2,(H,18,23)(H,24,25)(H,19,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089385 (CHEMBL3577967) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccccc2Cl)[nH]1 Show InChI InChI=1S/C17H13ClN4O3S/c18-12-7-3-4-8-13(12)19-14(23)9-26-17-20-15(21-22-17)10-5-1-2-6-11(10)16(24)25/h1-8H,9H2,(H,19,23)(H,24,25)(H,20,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089386 (CHEMBL3577968) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2cccc(Cl)c2)[nH]1 Show InChI InChI=1S/C17H13ClN4O3S/c18-10-4-3-5-11(8-10)19-14(23)9-26-17-20-15(21-22-17)12-6-1-2-7-13(12)16(24)25/h1-8H,9H2,(H,19,23)(H,24,25)(H,20,21,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089387 (CHEMBL3577969) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccccc2[N+]([O-])=O)[nH]1 Show InChI InChI=1S/C17H13N5O5S/c23-14(18-12-7-3-4-8-13(12)22(26)27)9-28-17-19-15(20-21-17)10-5-1-2-6-11(10)16(24)25/h1-8H,9H2,(H,18,23)(H,24,25)(H,19,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089389 (CHEMBL3577962) Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2nc3ccccc3[nH]2)[nH]1 Show InChI InChI=1S/C18H14N6O3S/c25-14(21-17-19-12-7-3-4-8-13(12)20-17)9-28-18-22-15(23-24-18)10-5-1-2-6-11(10)16(26)27/h1-8H,9H2,(H,26,27)(H,22,23,24)(H2,19,20,21,25)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089395 (CHEMBL3577972) Show SMILES OC(=O)CCc1nnc(SCC(=O)Nc2nc3ccccc3[nH]2)[nH]1 Show InChI InChI=1S/C14H14N6O3S/c21-11(18-13-15-8-3-1-2-4-9(8)16-13)7-24-14-17-10(19-20-14)5-6-12(22)23/h1-4H,5-7H2,(H,22,23)(H,17,19,20)(H2,15,16,18,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089394 (CHEMBL3577971) Show SMILES OC(=O)CCc1nnc(SCC(=O)Nc2ccccc2)[nH]1 Show InChI InChI=1S/C13H14N4O3S/c18-11(14-9-4-2-1-3-5-9)8-21-13-15-10(16-17-13)6-7-12(19)20/h1-5H,6-8H2,(H,14,18)(H,19,20)(H,15,16,17)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas veronii)	BDBM50089396 (CHEMBL3577974) Show SMILES OC(=O)CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2)[nH]1 Show InChI InChI=1S/C13H13ClN4O3S/c14-8-1-3-9(4-2-8)15-11(19)7-22-13-16-10(17-18-13)5-6-12(20)21/h1-4H,5-7H2,(H,15,19)(H,20,21)(H,16,17,18)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwest University Curated by ChEMBL					Assay Description Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...				ACS Med Chem Lett 6: 455-60 (2015) Article DOI: 10.1021/ml500534c BindingDB Entry DOI: 10.7270/Q2XP76P0
					More data for this Ligand-Target Pair