Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' AND taxid = 10116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Rattus norvegicus)	BDBM50305731 (CHEMBL604583 | N,4-dimethyl-N-(2-(thiophene-3-carb...) Show SMILES CN(c1ccccc1C(=O)c1ccsc1)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C19H17NO3S2/c1-14-7-9-16(10-8-14)25(22,23)20(2)18-6-4-3-5-17(18)19(21)15-11-12-24-13-15/h3-13H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at C5a receptor in rat RAW264.7 cells assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation afte...				Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Rattus norvegicus)	BDBM50305735 (CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...) Show SMILES CN(c1ccccc1N(C)S(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C22H24N2O4S2/c1-17-9-13-19(14-10-17)29(25,26)23(3)21-7-5-6-8-22(21)24(4)30(27,28)20-15-11-18(2)12-16-20/h5-16H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at C5a receptor in rat RAW264.7 cells assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation afte...				Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Rattus norvegicus)	BDBM50305737 (CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC=C)c1ccccc1N(CC=C)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C26H28N2O4S2/c1-5-19-27(33(29,30)23-15-11-21(3)12-16-23)25-9-7-8-10-26(25)28(20-6-2)34(31,32)24-17-13-22(4)14-18-24/h5-18H,1-2,19-20H2,3-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at C5a receptor in rat RAW264.7 cells assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation afte...				Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C
					More data for this Ligand-Target Pair