Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 1 (Rattus norvegicus) | BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Stephen F. Austin State University Curated by ChEMBL | Assay Description Inhibition of rat liver DNA topoisomerase 1 preincubated before addition of DNA | Bioorg Med Chem Lett 20: 2790-6 (2010) Article DOI: 10.1016/j.bmcl.2010.03.063 BindingDB Entry DOI: 10.7270/Q2J67HW5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 1 (Rattus norvegicus) | BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Stephen F. Austin State University Curated by ChEMBL | Assay Description Inhibition of rat liver DNA topoisomerase 1 treated simultaneously with DNA | Bioorg Med Chem Lett 20: 2790-6 (2010) Article DOI: 10.1016/j.bmcl.2010.03.063 BindingDB Entry DOI: 10.7270/Q2J67HW5 | |||||||||||
More data for this Ligand-Target Pair |