BindingDB PrimarySearch

Found 14 hits Enz. Inhib. hit(s) with Target = 'Elongation of very long chain fatty acids protein 6' AND taxid = 10090
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299971 (4-Fluoro-N-{[(+)-(4S)-2-oxo-6-(1H-pyrazol-5-yl)-4-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation index				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299971 (4-Fluoro-N-{[(+)-(4S)-2-oxo-6-(1H-pyrazol-5-yl)-4-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299963 (4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-4-yl)-4-(trif...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299948 (CHEMBL572158 \| N-{[(+)-6-Chloro-2-oxo-4-(trifluoro...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299965 (4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-1-yl)-4-(trif...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50293789 (3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of ELOVL6 in mouse H2.35 cells assessed as reduction in elongation index using [14C]palmitic acid as radiotracer after 4 hrs by radio-HPLC...				J Med Chem 52: 4111-4 (2009) Article DOI: 10.1021/jm900488k BindingDB Entry DOI: 10.7270/Q25D8SRQ
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299946 (1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50249892 (6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in african green monkey COS7 cells				J Med Chem 52: 3142-5 (2009) Article DOI: 10.1021/jm900391x BindingDB Entry DOI: 10.7270/Q20P0ZX6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299963 (4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-4-yl)-4-(trif...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation index				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299965 (4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-1-yl)-4-(trif...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation index				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50298968 ((1R,4S,6R*)-(+/-)-2-[(1-Methyl-1H-imidazol-4-yl)...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of C-terminal V5-epitope-tagged mouse ELOVL6 expressed in african green monkey COS7 cells				Bioorg Med Chem 17: 5639-47 (2009) Article DOI: 10.1016/j.bmc.2009.06.042 BindingDB Entry DOI: 10.7270/Q2WW7HQX
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50293789 (3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse ELOVL6 expressed in Pichia pastoris SND1168				J Med Chem 52: 4111-4 (2009) Article DOI: 10.1021/jm900488k BindingDB Entry DOI: 10.7270/Q25D8SRQ
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299948 (CHEMBL572158 \| N-{[(+)-6-Chloro-2-oxo-4-(trifluoro...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation index				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elongation of very long chain fatty acids protein 6 (Mus musculus)	BDBM50299946 (1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation index				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair