Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger' AND taxid = 8313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1/2/3 (Oryctolagus cuniculus)	BDBM50471141 (CHEMBL304627) Show SMILES [#6]-c1cc(-[#8]-c2ccc(Cl)cc2)c(cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7])S([#6])(=O)=O Show InChI InChI=1S/C16H16ClN3O4S/c1-9-7-13(24-11-5-3-10(17)4-6-11)14(25(2,22)23)8-12(9)15(21)20-16(18)19/h3-8H,1-2H3,(H4,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.				J Med Chem 40: 2017-34 (1997) Article DOI: 10.1021/jm960768n BindingDB Entry DOI: 10.7270/Q28055BJ
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger (Amphiuma tridactylum)	BDBM50270005 (5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...) Show SMILES CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N Show InChI InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Amphiuma tridactylum wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride ...				J Biol Chem 282: 19716-27 (2007) Article DOI: 10.1074/jbc.M701637200 BindingDB Entry DOI: 10.7270/Q2N0169D
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger (Amphiuma tridactylum)	BDBM16173 (3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(N)nc1N Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Amphiuma tridactylum wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride ...				J Biol Chem 282: 19716-27 (2007) Article DOI: 10.1074/jbc.M701637200 BindingDB Entry DOI: 10.7270/Q2N0169D
					More data for this Ligand-Target Pair