Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-hexosaminidase subunit alpha (Homo sapiens (Human)) | BDBM40765 (Iminocyclitol, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad. | Chem Biol 8: 701-11 (2001) Article DOI: 10.1016/S1074-5521(01)00045-X BindingDB Entry DOI: 10.7270/Q28C9TNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha (Homo sapiens (Human)) | BDBM50327038 ((3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Competitive inhibition of human beta-N-acetyl-D-hexosaminidase-A using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate assessed as re... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491619 (CHEMBL2385922) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491610 (CHEMBL2385089) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491612 (CHEMBL2385933) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491617 (CHEMBL2385932) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491613 (CHEMBL2385919) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491615 (CHEMBL2385935) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491606 (CHEMBL2385936) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491609 (CHEMBL2385934) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491618 (CHEMBL42904) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50024717 (2-(2-Dimethylamino-ethyl)-benzo[de]isoquinoline-1,...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491614 (CHEMBL2385939) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491601 (CHEMBL2333316) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491604 (CHEMBL2385941) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491605 (CHEMBL2385937) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491603 (CHEMBL2385921) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491611 (CHEMBL2385924) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491602 (CHEMBL2385923) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha (Homo sapiens (Human)) | BDBM40767 (Iminocyclitol, 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad. | Chem Biol 8: 701-11 (2001) Article DOI: 10.1016/S1074-5521(01)00045-X BindingDB Entry DOI: 10.7270/Q28C9TNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491616 (Naphthalimidopropylamine) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491607 (CHEMBL44709) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 3.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50491608 (CHEMBL2385925) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human beta-N-acetyl-D-hexosaminidase-A/B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate incubated for 10 mins pr... | ACS Med Chem Lett 4: 527-31 (2013) Article DOI: 10.1021/ml300475m BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha (Homo sapiens (Human)) | BDBM50394492 (CHEMBL1765471) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.63E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nankai University Curated by ChEMBL | Assay Description Inhibition of human Hex A using 4-MU-GlcNAc as substrate after 10 mins by Lineweaver Burk plot analysis | Bioorg Med Chem Lett 22: 6854-7 (2012) Article DOI: 10.1016/j.bmcl.2012.09.042 BindingDB Entry DOI: 10.7270/Q2KP838N | |||||||||||
More data for this Ligand-Target Pair |