Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A) dopamine receptor (RAT) | BDBM50016792 (8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-be...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was evaluated in vitro for the binding affinity to the rat striatal homogenate. | J Med Chem 32: 1431-5 (1989) BindingDB Entry DOI: 10.7270/Q2KD1WWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50016795 (3-Methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was evaluated in vitro for the binding affinity to the rat striatal homogenate. | J Med Chem 32: 1431-5 (1989) BindingDB Entry DOI: 10.7270/Q2KD1WWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007692 (8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.334 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its effect on dopamine saturation analysis | J Med Chem 29: 359-69 (1986) BindingDB Entry DOI: 10.7270/Q24X58C9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50033383 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a |
Wellcome Research Laboratories Curated by ChEMBL | Assay Description Binding affinity against dopamine receptor D1 in rat striatum using [3H]-SCH-23,390 as radioligand | J Med Chem 38: 3566-80 (1995) BindingDB Entry DOI: 10.7270/Q2GF0SJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50016794 (8-Chloro-5-(4-iodo-phenyl)-3-methyl-2,3,4,5-tetrah...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to the rat striatal homogenate | J Med Chem 32: 1431-5 (1989) BindingDB Entry DOI: 10.7270/Q2KD1WWT | |||||||||||
More data for this Ligand-Target Pair |