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Compile Data Set for Download or QSAR

Found 6 hits of kd for UniProtKB: P32211   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M4


(MOUSE)
BDBM50076089
PNG
((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12
Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1
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Article
n/an/an/a 11n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency of the compound assessed to inhibit cAMP levels in N1E-115 neuroblastoma cells, for blocking oxotremorine-M in functional assay for Muscarini...


Bioorg Med Chem Lett 2: 797-802 (1992)


Article DOI: 10.1016/S0960-894X(00)80534-X
BindingDB Entry DOI: 10.7270/Q22R3RKP
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5


(Mus musculus-MOUSE)
BDBM50028053
PNG
(Allyl-methyl-(1-phenyl-cyclohexyl)-amine | CHEMBL2...)
Show SMILES CN(CC=C)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C16H23N/c1-3-14-17(2)16(12-8-5-9-13-16)15-10-6-4-7-11-15/h3-4,6-7,10-11H,1,5,8-9,12-14H2,2H3
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n/an/an/a 1.50E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Angiotensin I converting enzyme


J Med Chem 27: 1267-71 (1984)


BindingDB Entry DOI: 10.7270/Q22Z14J3
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5


(Mus musculus-MOUSE)
BDBM83449
PNG
(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2
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n/an/an/a 9.10E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT binding to serotonin receptor of rat fundus membranes


J Med Chem 27: 1267-71 (1984)


BindingDB Entry DOI: 10.7270/Q22Z14J3
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5


(Mus musculus-MOUSE)
BDBM50028052
PNG
(Allyl-ethyl-(1-phenyl-cyclohexyl)-amine | CHEMBL23...)
Show SMILES CCN(CC=C)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C17H25N/c1-3-15-18(4-2)17(13-9-6-10-14-17)16-11-7-5-8-12-16/h3,5,7-8,11-12H,1,4,6,9-10,13-15H2,2H3
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n/an/an/a 1.40E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT binding to serotonin receptor of rat fundus membranes


J Med Chem 27: 1267-71 (1984)


BindingDB Entry DOI: 10.7270/Q22Z14J3
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5


(Mus musculus-MOUSE)
BDBM50028054
PNG
(Allyl-(1-phenyl-cyclohexyl)-amine | CHEMBL281855)
Show SMILES C=CCNC1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C15H21N/c1-2-13-16-15(11-7-4-8-12-15)14-9-5-3-6-10-14/h2-3,5-6,9-10,16H,1,4,7-8,11-13H2
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n/an/an/a 7.00E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT binding to serotonin receptor of rat fundus membranes


J Med Chem 27: 1267-71 (1984)


BindingDB Entry DOI: 10.7270/Q22Z14J3
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5


(Mus musculus-MOUSE)
BDBM50028051
PNG
(CHEMBL23626 | Diallyl-(1-phenyl-cyclohexyl)-amine)
Show SMILES C=CCN(CC=C)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C18H25N/c1-3-15-19(16-4-2)18(13-9-6-10-14-18)17-11-7-5-8-12-17/h3-5,7-8,11-12H,1-2,6,9-10,13-16H2
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n/an/an/a 2.50E+4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT binding to serotonin receptor of rat fundus membranes


J Med Chem 27: 1267-71 (1984)


BindingDB Entry DOI: 10.7270/Q22Z14J3
More data for this
Ligand-Target Pair