Compile Data Set for Download or QSAR

Found 3 hits of ec50 for UniProtKB: Q96SW2   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein cereblon (Homo sapiens (Human))	BDBM50404378 (CHEMBL5275511) Show SMILES COCCN(CC(O)=O)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C19H29N5O8S/c1-30-8-7-24(12-17(25)26)18(27)14(3-2-6-22-19(20)21)23-33(28,29)13-4-5-15-16(11-13)32-10-9-31-15/h4-5,11,14,23H,2-3,6-10,12H2,1H3,(H,25,26)(H4,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.				Citation and Details
					More data for this Ligand-Target Pair
Protein cereblon (Homo sapiens (Human))	BDBM50404379 (CHEMBL5184599) Show SMILES Cc1cc2ccc(cc2cc1C)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N(CC1CCCO1)CC(O)=O Show InChI InChI=1S/C25H35N5O6S/c1-16-11-18-7-8-21(13-19(18)12-17(16)2)37(34,35)29-22(6-3-9-28-25(26)27)24(33)30(15-23(31)32)14-20-5-4-10-36-20/h7-8,11-13,20,22,29H,3-6,9-10,14-15H2,1-2H3,(H,31,32)(H4,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	703	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.				Citation and Details
					More data for this Ligand-Target Pair
DNA-binding protein Ikaros/Protein cereblon (Homo sapiens (Human))	BDBM50557457 (CHEMBL4742712) Show SMILES FC(F)(C(=O)NCc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Protac activity at CRBN/IKZF1 (unknown origin) assessed as IKZF1 degradation				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01489 BindingDB Entry DOI: 10.7270/Q2F47STZ
					More data for this Ligand-Target Pair				3D Structure (crystal)