BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits of ec50 for monomerid = 292146   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM292146
PNG
(US10100057, Example 1 | US11046702, Example 1 | US...)
Show SMILES Fc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H14FN3O/c20-18-9-5-4-8-17(18)14-10-21-19-22-15(12-23(19)11-14)13-24-16-6-2-1-3-7-16/h1-12H,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 300n/an/an/a25



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...


US Patent US10100057 (2018)


BindingDB Entry DOI: 10.7270/Q2028TKW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM292146
PNG
(US10100057, Example 1 | US11046702, Example 1 | US...)
Show SMILES Fc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H14FN3O/c20-18-9-5-4-8-17(18)14-10-21-19-22-15(12-23(19)11-14)13-24-16-6-2-1-3-7-16/h1-12H,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 300n/an/an/an/a


TBA

Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2SQ93HC
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM292146
PNG
(US10100057, Example 1 | US11046702, Example 1 | US...)
Show SMILES Fc1ccccc1-c1cnc2nc(COc3ccccc3)cn2c1
Show InChI InChI=1S/C19H14FN3O/c20-18-9-5-4-8-17(18)14-10-21-19-22-15(12-23(19)11-14)13-24-16-6-2-1-3-7-16/h1-12H,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 300n/an/an/an/a



SK BIOPHARMACEUTICALS CO., LTD.

US Patent


Assay Description
Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...


US Patent US9745310 (2017)


BindingDB Entry DOI: 10.7270/Q24T6MG4
More data for this
Ligand-Target Pair