Compile Data Set for Download or QSAR

Found 4 hits of ec50 for monomerid = 307520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307520 ((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C24H37N5O4/c1-5-7-19(10-11-30)27-23-20(16(3)26-24(25)28-23)13-18-9-8-17(12-21(18)33-4)14-29(6-2)15-22(31)32/h8-9,12,19,30H,5-7,10-11,13-15H2,1-4H3,(H,31,32)(H3,25,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10562861 (2020) BindingDB Entry DOI: 10.7270/Q22F7QTT
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM307520 ((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C24H37N5O4/c1-5-7-19(10-11-30)27-23-20(16(3)26-24(25)28-23)13-18-9-8-17(12-21(18)33-4)14-29(6-2)15-22(31)32/h8-9,12,19,30H,5-7,10-11,13-15H2,1-4H3,(H,31,32)(H3,25,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...				US Patent US10150743 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K6N
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM307520 ((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C24H37N5O4/c1-5-7-19(10-11-30)27-23-20(16(3)26-24(25)28-23)13-18-9-8-17(12-21(18)33-4)14-29(6-2)15-22(31)32/h8-9,12,19,30H,5-7,10-11,13-15H2,1-4H3,(H,31,32)(H3,25,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description TLR8/NF-kB/SEAPorter™ HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the sec...				US Patent US10562861 (2020) BindingDB Entry DOI: 10.7270/Q22F7QTT
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM307520 ((S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...) Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC)CC(O)=O)cc1OC |r| Show InChI InChI=1S/C24H37N5O4/c1-5-7-19(10-11-30)27-23-20(16(3)26-24(25)28-23)13-18-9-8-17(12-21(18)33-4)14-29(6-2)15-22(31)32/h8-9,12,19,30H,5-7,10-11,13-15H2,1-4H3,(H,31,32)(H3,25,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. US Patent					Assay Description TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...				US Patent US10150743 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K6N
					More data for this Ligand-Target Pair