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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 349693   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucagon-like peptide 1 receptor


(Homo sapiens (Human))
BDBM349693
PNG
(2-[(4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridin-2-y...)
Show SMILES COCCn1c(CN2CCC(CC2)c2cccc(OCc3ccc(Cl)cc3F)n2)nc2ncc(nc12)C(O)=O
Show InChI InChI=1S/C27H28ClFN6O4/c1-38-12-11-35-23(33-25-26(35)32-22(14-30-25)27(36)37)15-34-9-7-17(8-10-34)21-3-2-4-24(31-21)39-16-18-5-6-19(28)13-20(18)29/h2-6,13-14,17H,7-12,15-16H2,1H3,(H,36,37)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 43n/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...


US Patent US10208019 (2019)


BindingDB Entry DOI: 10.7270/Q2WH2S4X
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor


(Homo sapiens (Human))
BDBM349693
PNG
(2-[(4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridin-2-y...)
Show SMILES COCCn1c(CN2CCC(CC2)c2cccc(OCc3ccc(Cl)cc3F)n2)nc2ncc(nc12)C(O)=O
Show InChI InChI=1S/C27H28ClFN6O4/c1-38-12-11-35-23(33-25-26(35)32-22(14-30-25)27(36)37)15-34-9-7-17(8-10-34)21-3-2-4-24(31-21)39-16-18-5-6-19(28)13-20(18)29/h2-6,13-14,17H,7-12,15-16H2,1H3,(H,36,37)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 680n/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...


US Patent US10208019 (2019)


BindingDB Entry DOI: 10.7270/Q2WH2S4X
More data for this
Ligand-Target Pair