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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50035601   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cystic fibrosis transmembrane conductance regulator


(Homo sapiens (Human))		BDBM50035601
PNG
(CHEMBL3356633)
Show SMILES O=C(Nc1ccc2ccccc2c1)c1c[nH]c2ccccc2c1=O
Show InChI InChI=1S/C20H14N2O2/c23-19-16-7-3-4-8-18(16)21-12-17(19)20(24)22-15-10-9-13-5-1-2-6-14(13)11-15/h1-12H,(H,21,23)(H,22,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 800n/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assay

J Med Chem 57: 9776-95 (2014)


Article DOI: 10.1021/jm5012808
BindingDB Entry DOI: 10.7270/Q2TH8P9K
More data for this
Ligand-Target Pair