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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50090121   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50090121
PNG
(CHEMBL3581544 | US9216988, 80)
Show SMILES CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(F)c1
Show InChI InChI=1S/C24H28Cl2FN3O3S/c1-17(31)28-7-9-29(10-8-28)23-6-5-19(24(27)14-23)15-30(22-3-2-4-22)34(32,33)16-18-11-20(25)13-21(26)12-18/h5-6,11-14,22H,2-4,7-10,15-16H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 40n/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...

ACS Med Chem Lett 6: 276-81 (2015)


Article DOI: 10.1021/ml500420y
BindingDB Entry DOI: 10.7270/Q2TT4SPB
More data for this
Ligand-Target Pair