Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Agonist activity against human melanocortin receptor hMC1R at 50% maximum cAMP accumulation | Bioorg Med Chem Lett 13: 133-7 (2002) BindingDB Entry DOI: 10.7270/Q2BV7H5F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Agonist activity in HEK293 cells transfected with human MC1R by cAMP accumulation | Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cells | Bioorg Med Chem Lett 15: 4910-4 (2005) Article DOI: 10.1016/j.bmcl.2005.08.012 BindingDB Entry DOI: 10.7270/Q28915D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Agonist activity against human melanocortin receptor hMC1R | Bioorg Med Chem Lett 13: 133-7 (2002) BindingDB Entry DOI: 10.7270/Q2BV7H5F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Agonist activity against human melanocortin receptor hMC4R | Bioorg Med Chem Lett 13: 133-7 (2002) BindingDB Entry DOI: 10.7270/Q2BV7H5F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Effective concentration for cAMP accumulation mediated by human Melanocortin 4 receptor in HEK293 cells | Bioorg Med Chem Lett 15: 4910-4 (2005) Article DOI: 10.1016/j.bmcl.2005.08.012 BindingDB Entry DOI: 10.7270/Q28915D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50121885 ((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation | Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7 | |||||||||||
More data for this Ligand-Target Pair |