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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50145136   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50145136
PNG
(CHEMBL3763963)
Show SMILES Cn1ccnc1C1C(Nc2cccc3c2c1n[nH]c3=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C21H16F3N5O/c1-29-10-9-25-19(29)16-17(11-5-7-12(8-6-11)21(22,23)24)26-14-4-2-3-13-15(14)18(16)27-28-20(13)30/h2-10,16-17,26H,1H3,(H,28,30)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/an/an/a 27n/an/an/an/a



BioMarin Pharmaceutical Inc.

Curated by ChEMBL


Assay Description
Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assay

J Med Chem 59: 335-57 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01498
BindingDB Entry DOI: 10.7270/Q2K35WJR
More data for this
Ligand-Target Pair