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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50187612   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50187612
PNG
(3,5-dimethoxy-N-(1,3-diphenyl-1H-pyrazol-5-yl)benz...)
Show SMILES COc1cc(OC)cc(c1)C(=O)Nc1cc(nn1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C24H21N3O3/c1-29-20-13-18(14-21(15-20)30-2)24(28)25-23-16-22(17-9-5-3-6-10-17)26-27(23)19-11-7-4-8-12-19/h3-16H,1-2H3,(H,25,28)
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MMDB

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Article
PubMed
n/an/an/an/a 2.04E+3n/an/an/an/a



Vanderbilt University School of Medicine

Curated by ChEMBL


Assay Description
Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes

J Med Chem 49: 3332-44 (2006)


Article DOI: 10.1021/jm051252j
BindingDB Entry DOI: 10.7270/Q2PR7VK1
More data for this
Ligand-Target Pair